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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2018.1
- 수록면
- 174 - 178 (5page)
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초록· 키워드
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Background and Purpose The literature indicates that obstructive sleep apnea (OSA) increasesthe risk of ischemic stroke. However, the causal relationship between OSA and ischemicstroke is not well established. This study examined whether preexisting OSA symptomsaffect the onset of acute ischemic stroke. Methods We investigated consecutive patients who were admitted with acute ischemicstroke, using a standardized protocol including the Berlin Questionnaire on symptoms of OSAprior to stroke. The collected stroke data included the time of the stroke onset, risk factors, andetiologic subtypes. The association between preceding OSA symptoms and wake-up stroke(WUS) was assessed using multivariate logistic regression analysis. Results We identified 260 subjects with acute ischemic strokes with a definite onset time, ofwhich 25.8% were WUS. The presence of preexisting witnessed or self-recognized sleep apneawas the only risk factor for WUS (adjusted odds ratio=2.055, 95% confidence interval=1.035–4.083, p=0.040). Conclusions Preexisting symptoms suggestive of OSA were associated with the occurrence ofWUS. This suggests that OSA contributes to ischemic stroke not only as a predisposing risk factorbut also as a triggering factor. Treating OSA might therefore be beneficial in preventingstroke, particularly that occurring during sleep.
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등록된 정보가 없습니다.
참고문헌 (28)
참고문헌 신청
Kernan WN / 2014 / Guidelines for the prevention of stroke in patients with stroke and transient ischemic attack: a guideline for healthcare professionals from the American Heart Association/American Stroke Association / Stroke 45:2160~2236
Yaggi HK / 2005 / Obstructive sleep apnea as a risk factor for stroke and death / N Engl J Med 353:2034~2041
Redline S / 2010 / Obstructive sleep apnea-hypopnea and incident stroke: the sleep heart health study / Am J Respir Crit Care Med 182:269~277
Kim Y / 2016 / Can continuous positive airway pressure reduce the risk of stroke in obstructive sleep apnea patients? A systematic review and meta-analysis / PLoS One 11:e0146317
Mackey J / 2011 / Population-based study of wake-up strokes / Neurology 76:1662~1667
Yaggi HK / 2005 / Obstructive sleep apnea as a risk factor for stroke and death / N Engl J Med 353:2034~2041
Redline S / 2010 / Obstructive sleep apnea-hypopnea and incident stroke: the sleep heart health study / Am J Respir Crit Care Med 182:269~277
Kim Y / 2016 / Can continuous positive airway pressure reduce the risk of stroke in obstructive sleep apnea patients? A systematic review and meta-analysis / PLoS One 11:e0146317
Mackey J / 2011 / Population-based study of wake-up strokes / Neurology 76:1662~1667
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