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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2016.1
- 수록면
- 274 - 281 (8page)
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초록· 키워드
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Neurolymphomatosis (NL) defned as infltration of the central nervous system or the peripheral nervous system (PNS) by malignant lymphoma cells is a rare clinical entity. However, the increasing use of fuorodeoxyglucose positron-emission tomography (FDG-PET) and magnetic resonance imaging in evaluating PNS disorders is resulting in; this condition being recognized more frequently. Here; we report fve NL patients and review the current literature. We report five patients with non-Hodgkin’s lymphoma (NHL) and NL, all of whom were men aged 47–69 years. Te clinical presentation varied from symmetrical peripheral neuropathy to mononeuropathy. Peripheral neuropathy was the presenting manifestation of a systemic lymphoma in two patients (40%). Neuroimaging as well as whole-body FDG-PET helped in determining the correct diagnosis in all of the patients. NL is an unusual presentation of NHL resulting from infltration of the PNS by malignant lymphomatous cells. While evaluating peripheral neuropathy, a high degree of suspicion of NL is required since the presenting symptoms vary, conventional radiology has only modest sensitivity, and a pathological diagnosis is ofen difcult. FDG-PET helps in the early diagnosis and treatment of this condition.
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등록된 정보가 없습니다.
참고문헌 (17)
참고문헌 신청
Petluri G / 2014 / Neurolymphomatosis: a rare cause of multiple mononeuropathy / World J Neurosci 4:190~193
Peterson J / 2014 / Positron emission tomography/computerized tomography imaging of multiple focus of neurolymphomatosis / Indian J Nucl Med 29:252~253
Vallat JM / 1995 / Non-Hodgkin malignant lymphomas and peripheral neuropathies--13 cases / Brain 118(Pt 5):1233~1245
Viala K / 2008 / Neuropathy in lymphoma: a relationship between the pattern of neuropathy, type of lymphoma and prognosis? / J Neurol Neurosurg Psychiatry 79:778~782
Vital C / 1990 / Peripheral neuropathies and lymphoma without monoclonal gammopathy:a new classification / J Neurol 237:177~185
Peterson J / 2014 / Positron emission tomography/computerized tomography imaging of multiple focus of neurolymphomatosis / Indian J Nucl Med 29:252~253
Vallat JM / 1995 / Non-Hodgkin malignant lymphomas and peripheral neuropathies--13 cases / Brain 118(Pt 5):1233~1245
Viala K / 2008 / Neuropathy in lymphoma: a relationship between the pattern of neuropathy, type of lymphoma and prognosis? / J Neurol Neurosurg Psychiatry 79:778~782
Vital C / 1990 / Peripheral neuropathies and lymphoma without monoclonal gammopathy:a new classification / J Neurol 237:177~185
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