메뉴 건너뛰기
.. 내서재 .. 알림
소속 기관/학교 인증
인증하면 논문, 학술자료 등을  무료로 열람할 수 있어요.
한국대학교, 누리자동차, 시립도서관 등 나의 기관을 확인해보세요
(국내 대학 90% 이상 구독 중)
로그인 회원가입 고객센터 ENG
주제분류

추천
검색

논문 기본 정보

자료유형
학술저널
저자정보
저널정보
대한신경과학회 Journal of Clinical Neurology Journal of Clinical Neurology 제10권 제3호
발행연도
2014.1
수록면
203 - 209 (7page)

이용수

표지
📌
연구주제
📖
연구배경
🔬
연구방법
🏆
연구결과
AI에게 요청하기
추천
검색

초록· 키워드

오류제보하기
Background and Purpose It has been shown that sleep problems in Alzheimer’s disease (AD)are associated with cognitive impairment and behavioral problems. In fact, most of studies havefounded that daytime sleepiness is significantly correlated with cognitive decline in AD. However, a few studies have also shown that nighttime sleep problems are associated with cognitivefunction and behavioral symptoms in AD. Accordingly, the aim of this study was to evaluate theeffects of nighttime sleep on cognition and behavioral and psychological symptoms of dementia(BPSD) in AD. Methods The study population comprised 117 subjects: 63 AD patients and 54 age- and sexmatched non-demented elderly subjects. Detailed cognitive functions and behavioral symptomswere measured using the Seoul Neuropsychological Screening Battery (SNSB) and the Koreanversion of the Neuropsychiatric Inventory (NPI-K). Sleep characteristics were evaluated usingthe Korean version of the Pittsburgh Sleep Quality Index (PSQI-K). The correlations betweenPSQI-K and SNSB scores and between PSQI-K and NPI-K scores were analyzed. Results In AD patients, sleep latency was found to be negatively correlated with praxis (p=0.041), Rey-Osterrieth Complex Figure Test (RCFT) immediate recall (p=0.041), and RCFTrecognition (p=0.008) after controlling for age and education, while sleep duration and sleep efficiency were positively correlated with praxis (p=0.034 and p=0.025, respectively). Althoughno significant correlation was found between PSQI-K and NPI-K scores, sleep disturbance andtotal PSQI-K scores were found to be significantly associated with apathy/indifference in AD. Conclusions Sleep problems such as prolonged sleep duration, sleep latency, and poor sleepefficiency in AD patients were correlated with cognitive dysfunction, and especially frontal executive and visuospatial functions, and BPSD. These findings suggest that treatment of nighttime sleep problems might improve cognition and behavioral symptoms in AD patients.

목차

등록된 정보가 없습니다.

참고문헌 (34)

참고문헌 신청

이 논문의 저자 정보

최근 본 자료

전체보기

댓글(0)

0