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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2015.1
- 수록면
- 149 - 156 (8page)
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Background and Purpose Carotid artery stenting (CAS) is emerging as an alternative to carotid endarterectomy for the treatment of carotid artery stenosis (CS), but the efect of CAS onthe cognitive function of patients with severe CS has not been fully investigated. Te aim ofthis study was to use comprehensive neuropsychological tests to determine the efect of CASon cognitive function from baseline to 3 months postprocedure in patients with severe CS.
Methods Tirty-one patients due to undergo CAS due to high-grade CS (≥70%) and 11control subjects who were diagnosed with CS, but who did not undergo CAS, and who visitedthe clinic or emergency room between February 2009 and February 2012 were recruited consecutively at baseline (i.e., pre-CAS). Follow-up neuropsychological evaluations afer 3 monthswere completed by 23 of the 31 patients who underwent CAS, and by 10 of the 11 control subjects. Te primary cognitive outcome was assessed using a neuropsychological test containingsubcategories designed to test general cognitive function, attention, visuospatial function, language and related functions, memory, and frontal lobe/executive function.
Results Of the 23 patients undergoing CAS who completed the 3-month follow-up tests, 12had asymptomatic CS. During the 3-month follow-up period, the patients who underwent CASand those with asymptomatic CS achieved similar results to the control group on all cognitivetests. However, symptomatic CS patients (n=11) who underwent CAS exhibited improvements in visuospatial function (p=0.046) and total Seoul Neuropsychological Screening Battery-Dementia Version scores (p=0.010) in comparison with both the asymptomatic CS patients and the control group. Conclusions Te fndings of this study suggest that CAS has a positive efect on cognitivefunction in patients with symptomatic CS over a 3-month follow-up period. A long-term, multicenter, prospective case-control study would be helpful to predict quality of life and prognoses for patients undergoing CAS.
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참고문헌 (22)
참고문헌 신청
Aleksic M / 2006 / Cognitive function remains unchanged after endarterectomy of unilateral internal carotid artery stenosis under local anaesthesia / Eur J Vasc Endovasc Sur
De Rango P / 2008 / The role of carotid artery stenting and carotid endarterectomy in cognitive performance:a systematic review / Stroke 39 : 3116 ~ 3127
Folstein MF / 1975 / “Mini-mental state”. A practical method for grading the cognitive state of patients for the clinician / J Psychiatr Res 12 : 189 ~ 198
Ghogawala Z / 2008 / Cognitive outcomes after carotid revascularization: the role of cerebral emboli and hypoperfusion / Neurosurgery 62 : 385 ~ 395
Goldstein LB / 2006 / Primary prevention of ischemic stroke: a guideline from the American Heart Association/American Stroke Association Stroke Council: cosponsored by the At
De Rango P / 2008 / The role of carotid artery stenting and carotid endarterectomy in cognitive performance:a systematic review / Stroke 39 : 3116 ~ 3127
Folstein MF / 1975 / “Mini-mental state”. A practical method for grading the cognitive state of patients for the clinician / J Psychiatr Res 12 : 189 ~ 198
Ghogawala Z / 2008 / Cognitive outcomes after carotid revascularization: the role of cerebral emboli and hypoperfusion / Neurosurgery 62 : 385 ~ 395
Goldstein LB / 2006 / Primary prevention of ischemic stroke: a guideline from the American Heart Association/American Stroke Association Stroke Council: cosponsored by the At
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