지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
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In this paper, we described 23 cases of animal experiment with our pneumatic ventricular assist device and new durability-improvement method. The blood pump consists of blood housing, and back plate made by the injection moldingof isoplast, and the diaphragm fabricated by dipping of polyurethane solution onto the aluminum mold. Its volume was 75 ml and in-vitro test showed that maximum output was 4.5 l/min at the 100 mmHg. The adult female sheep with weight of 50 + 10 kg were employed for the in-vivo experiments and the mean blood flow was sustained at 3.0 l/min. 4 animals survived more than 15 days and the longest survival time was 28 days. In the prior 10 cases, the major causes of death were the tearing of diaphragm at the diaphragm to blood housing junction. By the new mesh and alumina ball milling methods, the durability was enhanced, and its qualitative and quantitative improvement was proved via the in-vivo and in-vitro methods. Animal experiments demonstrated that all the physiologic parameters were maintained within the permissible ranges and no thrombus formation was observed through the visual and blood test. The in-vivo experiments demonstrated our pneumatic ventricular assist device to be one month's bridge to transplantation device.
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참고문헌 (20)
참고문헌 신청
/ / A Novel Diaphragm to Housing Junction Adhesion Method Alumina Mall Milling
/ 1958 / Permanent substitute for valves and hearts 4 : 230 ~ 235
/ 1971 / Left ventricular bypass pump for cardiacassistance:clinical experience 27 : 3 ~ 11
/ 1981 / Critical analysis of intra-aortic balloon counterpulsation and transapical left ventricular bypass in the sufficient and insufficient circulation 29 : 17 ~ 31
/ 1987 / Percutaneous cardiopulmonary bypass with a synchronous pulsatile pump combines effective unloading with ease of application 93 : 358 ~ 365
/ 1958 / Permanent substitute for valves and hearts 4 : 230 ~ 235
/ 1971 / Left ventricular bypass pump for cardiacassistance:clinical experience 27 : 3 ~ 11
/ 1981 / Critical analysis of intra-aortic balloon counterpulsation and transapical left ventricular bypass in the sufficient and insufficient circulation 29 : 17 ~ 31
/ 1987 / Percutaneous cardiopulmonary bypass with a synchronous pulsatile pump combines effective unloading with ease of application 93 : 358 ~ 365
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