지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2012.1
- 수록면
- 429 - 432 (4page)
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초록· 키워드
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The -D- phenotype is a rare Rh phenotype that strongly expresses D antigen without C, c, E, or e antigens. In -D- phenotype individuals, anti-Rh17 (Hro) is commonly found if there is a history of pregnancy or transfusion with red blood cells (RBCs) that express C, c, E, or e antigens. We report the first case of a -D- phenotype patient with multiple Rh antibodies including anti-Rh17 who had a history of two occasions of transfusion with eight random donor platelet concentrates two and six years ago. We found that a trivial amount of RBCs in the platelet components was able to trigger sensitization to RBC antigens, especially the highly immunogenic and clinically significant Rh antigens, including C, c, E, e or CcEe polypeptides. To avoid unnecessary sensitization and to minimize the risk of hemolytic transfusion reactions in patients with this rare Rh phenotype, a modified strategy for pretransfusion screenings needs to be discussed in the field of transfusion medicine.
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참고문헌 (19)
참고문헌 신청
Aref K / 2002 / Successful perinatal management of hydrops fetalis due to hemolytic disease associated with D-- maternal phenotype / J Perinatol 22 : 667 ~ 668
Avent ND / 2000 / The Rh blood group system: a review / Blood 95 : 375 ~ 387
Brumit MC / 2002 / Moderate hemolytic disease of the newborn (HDN) due to anti-Rh17 produced by a black female with an e variant phenotype / Immunohematology 18 : 40 ~ 42
Choi KH / 2001 / The preparation of frozen red blood cells and a procedure for deglycerolizing frozen RBCs using COBE 2991 blood cell processor / Korean J Blood Transfus 12
De Vooght KM / 2012 / Successful transfusion care for a patient with the Rhesus -D- phenotype and antibodies against Rh17 and two additional alloantibodies / Ann Hematol 91
Avent ND / 2000 / The Rh blood group system: a review / Blood 95 : 375 ~ 387
Brumit MC / 2002 / Moderate hemolytic disease of the newborn (HDN) due to anti-Rh17 produced by a black female with an e variant phenotype / Immunohematology 18 : 40 ~ 42
Choi KH / 2001 / The preparation of frozen red blood cells and a procedure for deglycerolizing frozen RBCs using COBE 2991 blood cell processor / Korean J Blood Transfus 12
De Vooght KM / 2012 / Successful transfusion care for a patient with the Rhesus -D- phenotype and antibodies against Rh17 and two additional alloantibodies / Ann Hematol 91
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