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Objective: To evaluate the effects of patella taping on pain and disability in symptomatic knee osteoarthritis (OA). Method: Using a within-subjects study design, 54 patients were tested under three conditions in random order: untaped, wearing therapeutic knee tape and wearing control knee tape. Outcome measure was pain as measured by visual analogue scale and disability as measured by walking speed, timed up and go test, and step test. Results: The therapeutic tape significantly reduced pain, when compared with the control and untaped conditions (p<0.05). Also significant improvement in disability was ob-served on timed up and go test and step test in therapeutic tape compared with the control and untaped conditions (p<0.05). But there was no significant difference on walking speed among three conditions (p>0.05). A significant association between change of pain in stairs and lateral patellofemoral joint space was evident (r=0.503, p<0.05). Conclusion: Therapeutic knee tape is a simple, inexpensive strategy that increases the treatment options for therapists and patients in the conservative management of knee OA.

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