지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2018.1
- 수록면
- 35 - 41 (7page)
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초록· 키워드
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Objective To investigate the current status of pharmacotherapy prescribed by physiatrists in Korea for cognitive-behavioral disorder. Methods A cross-sectional study was performed by mailing questionnaires to 289 physiatrists working at teaching hospitals. Items on the questionnaire evaluated prescribing patterns of 16 drugs related to cognitive-behavioral therapy, the status of combination pharmacotherapy, and tools for assessing target symptoms. Results Fifty physiatrists (17.3%) including 24 (48%) specializing in neurorehabilitation completed the questionnaires. The most common target symptom was attention deficit (29.5%). Donepezil and methylphenidate (96.0%) were the most frequently prescribed drugs for cognitive-behavioral improvement. Mostly, a combination of two drugs was prescribed (38.0%), and the most common combination therapy included donepezil plus methylphenidate (19.1%). Pharmacotherapy for cognitive-behavioral disorder after brain injury was typically initiated within 2 months (69.5%). A follow-up assessment was usually performed at 1 month after treatment initiation (31.0%). The most common reason for treatment discontinuation was improvement of target symptoms (37.8%). The duration of pharmacotherapy was 3–12 months (57.7%), 1–2 years (17.9%), or 1–2 months (13.6%). Conclusion According to the survey, combination pharmacotherapy is preferred to monotherapy for the treatment of cognitive-behavioral disorder in patients with brain injury. Physiatrists expressed diverse views on the definition of target symptoms, prescribing patterns, and the status of drug combination therapy. Guidelines are needed for cognitive-behavioral pharmacotherapy. Further research should investigate drug costs and aim to reduce polypharmacy and adverse drug reactions.
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등록된 정보가 없습니다.
참고문헌 (13)
참고문헌 신청
Rah UW / 2014 / Clinical practice guideline for stroke rehabilitation in Korea 2012 / Brain Neurorehabil 7(Suppl 1):S1~S75
Francisco GE / 2007 / Pharmacological management of neurobehavioural sequelae of traumatic brain injury: a survey of current physiatric practice / Brain Inj 21:1007~1014
Sadowsky CH / 2012 / Guidelines for the management of cognitive and behavioral problems in dementia / J Am Board Fam Med 25:350~366
Liepert J / 2016 / Update on pharmacotherapy for stroke and traumatic brain injury recovery during rehabilitation / Curr Opin Neurol 29:700~705
Gallacher KI / 2014 / Stroke, multimorbidity and polypharmacy in a nationally representative sample of 1,424,378 patients in Scotland: implications for treatment burden / BMC Med 12:151
Francisco GE / 2007 / Pharmacological management of neurobehavioural sequelae of traumatic brain injury: a survey of current physiatric practice / Brain Inj 21:1007~1014
Sadowsky CH / 2012 / Guidelines for the management of cognitive and behavioral problems in dementia / J Am Board Fam Med 25:350~366
Liepert J / 2016 / Update on pharmacotherapy for stroke and traumatic brain injury recovery during rehabilitation / Curr Opin Neurol 29:700~705
Gallacher KI / 2014 / Stroke, multimorbidity and polypharmacy in a nationally representative sample of 1,424,378 patients in Scotland: implications for treatment burden / BMC Med 12:151
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