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자료유형
학술저널
저자정보
저널정보
대한재활의학회 Annals of Rehabilitation Medicine Annals of Rehabilitation Medicine 제34권 제2호
발행연도
2010.1
수록면
179 - 184 (6page)

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Objective: To investigate the electrophysiological changes after botulinum toxin type A injection in children with cerebral palsy. Method: Sixteen children with spastic cerebral palsy enrolled in the study. Botulinum toxin type A (DysportⓇ) was injected into gastrocnemius muscles. Electrophysiological assessments included the compound motor action potential of the tibial nerve, the sensory nerve action potential of the sural nerve, the H-reflex and the T-reflex before injection, and at 2 weeks and 4 weeks after the injection. Modified Ashworth scale was used to evaluate spasticity before, 2 weeks and 4 weeks after the injection. Results: Modified Ashworth scale of the ankle decreased at 2 weeks and 4 weeks after injection. The amplitude of the H-reflex and Hmax/Mmax ratio decreased significantly at 4 weeks. The amplitude of the T-reflex decreased at 2 weeks and 4 weeks. The correlation between changes in modified Ashworth scale of the ankle and the changes in electrophysiological parameters at 4 weeks after injection were not significant. Conclusion: The change in T-reflex is faster than the change of H-reflex and Hmax/Mmax ratio after botulinum toxin A injection in children with cerebral palsy. Electrophysiological tests could quantify the change in spasticity after botulinum toxin injection. (J Korean Acad Rehab Med 2010; 34: 179-184)

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