지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한정신약물학회 Clinical Psychopharmacology and Neuroscience Clinical Psychopharmacology and Neuroscience 제10권 제2호
- 발행연도
- 2012.1
- 수록면
- 110 - 116 (7page)
이용수
초록· 키워드
오류제보하기
Objective: Morningness/eveningness (M/E) is a stable characteristic of individuals. Circadian rhythms are altered in episodes of mood disorder. Mood disorder patients were more evening-type than normal population. In this study, we compared the characteristics of M/E among the 257 patients with bipolar I disorder (BPD1), bipolar II disorder (BPD2) and major depressive disorder,recurrent (MDDR).
Methods: M/E was evaluated using the Korean version of the composite scale of morningness (CS). Factor analysis was done to extract specific elements of circadian rhythm (morning preference, morning alertness, and evening tiredness). The total score and scores for factors and individual items of CS were compared in order to evaluate differences among the three different diagnostic groups. Factor scores of CS were different among the diagnostic groups.
Results: BPD1 subjects had a higher score for evening tiredness than BPD2 subjects (p=0.060), and BPD1 subjects had a significantly higher score for morning alertness than subjects with MDDR (p=0.034). This difference was even more profound for the representative item scores of each factor; item 2 of CS for evening tiredness (BPD1＞BPD2, p=0.007) and item 5 of CS for morning alertness (BPD1＞MDDR, p=0.002). Total score of CS were not different among 3 diagnostic groups.
Conclusion: Circadian rhythm characteristics measured by CS were different among BPD1, BPD2, and MDDR. BPD2 showed more eveningness than BPD1. MDDR showed less morningness than BPD1. CS would be a reasonable endophenotype associated with mood disorders. More studies with large sample size of mood disorders on M/E are warranted.
목차
등록된 정보가 없습니다.
참고문헌 (24)
참고문헌 신청
[학술지(정기간행물
Amorim P / 1998 / DSM-IH-R psychotic disorders: procedural validity of the Mini International Neuropsychiatric Interview (MINI). Concordance and causes for discordance with t
Baehr EK / 2000 / Individual differences in the phase and amplitude of the human circadian temperature rhythm: with an emphasis on morningness-eveningness / J Sleep Res 9 : 1
Benedetti F / 2008 / Clock genes beyond the clock: CLOCK genotype biases neural correlates of moral valence decision in depressed patients / Genes Brain Behav 7 : 20 ~ 25
Duffy JF / 2001 / Association of intrinsic circadian period with morningness-eveningness, usual wake time, and circadian phase / Behav Neurosci 115 : 895 ~ 899
Amorim P / 1998 / DSM-IH-R psychotic disorders: procedural validity of the Mini International Neuropsychiatric Interview (MINI). Concordance and causes for discordance with t
Baehr EK / 2000 / Individual differences in the phase and amplitude of the human circadian temperature rhythm: with an emphasis on morningness-eveningness / J Sleep Res 9 : 1
Benedetti F / 2008 / Clock genes beyond the clock: CLOCK genotype biases neural correlates of moral valence decision in depressed patients / Genes Brain Behav 7 : 20 ~ 25
Duffy JF / 2001 / Association of intrinsic circadian period with morningness-eveningness, usual wake time, and circadian phase / Behav Neurosci 115 : 895 ~ 899
이 논문의 저자 정보
최근 본 자료
댓글(0)
0