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논문 기본 정보

자료유형
학술저널
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대한정신약물학회 Clinical Psychopharmacology and Neuroscience Clinical Psychopharmacology and Neuroscience 제12권 제3호
발행연도
2014.1
수록면
235 - 239 (5page)

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Tourette syndrome consists of multiple motor tics and one or more vocal tics. Psychopathology occurs in approximately 90%of Tourette syndrome patients, with attention-deficit/hyperactivity, mood, and obsessive-compulsive disorders being common. Additionally, Tourette syndrome and bipolar disorder may be related in some individuals. However, it is unclear why bipolardisorder may be overrepresented in Tourette syndrome patients, and more research is needed. Herein, we report the caseof a 15-year-old boy diagnosed with both Tourette syndrome and bipolar disorder, whose symptoms improved with aripiprazole,atomoxetine, and valproate. The patient was diagnosed with Tourette syndrome at 8 years of age when he developed tics andexperienced his first depressive episode. The patient had a poor response to a variety of antidepressants and anti-ticmedications. A combination of valproate and aripiprazole stabilized both the patient’s tics and mood symptoms. It is importantto assess individuals with Tourette syndrome for other disorders, including bipolar disorder. The treatment of children and adolescentswith both Tourette syndrome and bipolar disorder is an important clinical issue.

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