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자료유형
학술저널
저자정보
저널정보
대한정신약물학회 Clinical Psychopharmacology and Neuroscience Clinical Psychopharmacology and Neuroscience 제12권 제3호
발행연도
2014.1
수록면
240 - 242 (3page)

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Post-traumatic stress disorder (PTSD) is a pathological response to trauma characterized by frequent recollections, recurrentnightmares, and flashbacks of the traumatic event(s). To date, the precise mechanisms underlying the development of PTSDremain unknown. Several studies have suggested that antiepileptic drugs, such as gabapentin and lamotrigine, may be effectivein the treatment of PTSD symptoms. We report on a 15-year-old Japanese female junior high school student who developedPTSD symptoms following repeated teasing from male classmates. Additionally, we underscore the beneficial effects of treatmentwith gabapentin and lamotrigine on flashbacks and nightmares. This patient developed PTSD symptoms after repeated teasingfrom male classmates at school. Her flashbacks and nightmares were treated with a combination of gabapentin and lamotrigine. After recovery, treatment with lamotrigine alone controlled her symptoms. Our observations suggest that a process of sensitizationmay be involved in the development of PTSD symptoms. Additionally, gabapentin and/or lamotrigine were effective in the treatmentof flashbacks and nightmares in this patient. Thus, doctors should consider using these anti-epileptic drugs as an alternativeapproach to treating PTSD symptoms.

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