지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한정신약물학회 Clinical Psychopharmacology and Neuroscience Clinical Psychopharmacology and Neuroscience 제13권 제3호
- 발행연도
- 2015.1
- 수록면
- 275 - 282 (8page)
이용수
초록· 키워드
오류제보하기
Objective: Early treatment choice is critical in first-episode schizophrenia-spectrum disorders. The purpose of this study was to describe prescribing trends of antipsychotics use in patients with first-episode schizophrenia in 2005 and 2010, respectively.
Methods: We reviewed the medical records of newly treated patients with schizophrenia from a university psychiatric hospital in 2005 (n=47) and 2010 (n=52). We defined patients as receiving a high antipsychotic dose if their ratio of prescribed daily dose (PDD) to defined daily dose (DDD) was greater than 1.5.
Results: The rates of high-dose antipsychotic prescription were 61.7% and 53.8% in 2005 and 2010, respectively. The rates of antipsychotic polypharmacy were 34.6% in 2005 and 34.0% in 2010. The most common first-prescribed antipsychotics were (in descending order of prescription frequency) olanzapine, risperidone, aripiprazole, and haloperidol in 2005 and risperidone, quetiapine, paliperidone, and olanzapine in 2010. High-dose antipsychotics were significantly associated with antipsychotic polypharmacy (odds ratio=23.97; p＜0.01). More individuals were treated with mood stabilizers in 2010 than in 2005 (p=0.003).
Conclusion: The practice of prescribing high-dose antipsychotics and associated antipsychotic polypharmacy were common even for initial treatment of first-episode schizophrenia in 2005 and 2010. In 2010, the list of the most common first-prescribed antipsychotics changed, and the use of mood stabilizers increased in non-affective schizophrenia.
목차
등록된 정보가 없습니다.
참고문헌 (53)
참고문헌 신청
Takahashi H. / 2006 / Switching to risperidone after unsuccessful treatment of olanzapine in the first-episode schizophrenia : an open trial / Prog Neuropsychopharmacol Biol Psychiatry 30:1067~1072
Schwartz TL. / 2011 / Treatment strategies for dosing the second generation antipsychotics / CNS Neurosci Ther 17:110~117
Agid O. / 2013 / Antipsychotic response in first-episode schizophrenia : efficacy of high doses and switching / Eur Neuropsychopharmacol 23:1017~1022
Lass J. / 2008 / Pharmacotherapy of first episode psychosis in Estonia : comparison with national and international treatment guidelines / J Clin Pharm Ther 33:165~173
Wu CS. / 2012 / Trends in treatment of newly treated schizophrenia-spectrum disorder patients in Taiwan from 1999 to 2006 / Pharmacoepidemiol Drug Saf 21:989~996
Schwartz TL. / 2011 / Treatment strategies for dosing the second generation antipsychotics / CNS Neurosci Ther 17:110~117
Agid O. / 2013 / Antipsychotic response in first-episode schizophrenia : efficacy of high doses and switching / Eur Neuropsychopharmacol 23:1017~1022
Lass J. / 2008 / Pharmacotherapy of first episode psychosis in Estonia : comparison with national and international treatment guidelines / J Clin Pharm Ther 33:165~173
Wu CS. / 2012 / Trends in treatment of newly treated schizophrenia-spectrum disorder patients in Taiwan from 1999 to 2006 / Pharmacoepidemiol Drug Saf 21:989~996
함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Effectiveness in Switching from Antipsychotic Polypharmacy to Monotherapy in Patients with Schizophrenia: A Case Series
Clinical Psychopharmacology and Neuroscience
2020 .01
-
양극성장애에서 Antipsychotics의 사용 전략
신경정신의학
2018 .01
-
Exploring Hidden Issues in the Use of Antipsychotic Polypharmacy in the Treatment of Schizophrenia
Clinical Psychopharmacology and Neuroscience
2021 .11
-
Understanding of Antipsychotics in Elderly Patients with Dementia
Dementia and Neurocognitive Disorders(대한치매학회지)
2015 .01
-
항정신병약물의 생물학적 기전 최신 지견
신경정신의학
2019 .01
-
항정신병약물에 의한 대사부작용에 대한 이론과 대처방안
신경정신의학
2019 .01
-
항정신병 약물의 병용요법을 사용 중인 환자들에서 아리피프라졸 장기 지속형 주사제의 효능
생물치료정신의학
2024 .10
-
조현병 환자에서 항정신병약물 유지치료 시 치료결과에 대한 연구
대한조현병학회지
2017 .10
-
Quantitative Resting State Electroencephalography in Patients with Schizophrenia Spectrum Disorders Treated with Strict Monotherapy Using Atypical Antipsychotics
Clinical Psychopharmacology and Neuroscience
2021 .01
-
Assessment of the Latent Adverse Events of Antipsychotic Treatment Using a Subjective Questionnaire in Japanese Patients with Schizophrenia
Clinical Psychopharmacology and Neuroscience
2017 .01
-
‘2019 한국형 조현병 약물치료 지침서’에 따른 조현병에서 동반증상 및 부작용의 치료
대한조현병학회지
2019 .01
-
Diabetic Ketoacidosis Associated With Second Generation Antipsychotics: A Case Study and Review of Literature
PSYCHIATRY INVESTIGATION
2024 .02
-
A Systemic Review and Experts’ Consensus for Long-acting Injectable Antipsychotics in Bipolar Disorder
Clinical Psychopharmacology and Neuroscience
2015 .01
-
Evaluation of Paraoxonase, Arylesterase and Malondialdehyde Levels in Schizophrenia Patients Taking Typical, Atypical and Combined Antipsychotic Treatment
Clinical Psychopharmacology and Neuroscience
2016 .01
-
노인환자의 항정신병 약물 원외처방 내역에 미친 영향 요인 분석
한국임상약학회지
2021 .12
-
The Prescribing Patterns of Antipsychotic Drugs and Antiparkinsonian Drugs in Elderly Patients with Dementia
한국임상약학회지
2020 .01
-
Prescription Patterns for Bipolar Disorder in Asian Countries: Findings from Research on Asian Prescription Pattern-Bipolar Disorder
Clinical Psychopharmacology and Neuroscience
2022 .02
-
Neutropenia with Multiple Antipsychotics Including Dose Dependent Neutropenia with Lurasidone
Clinical Psychopharmacology and Neuroscience
2017 .01
-
Antipsychotic Medication in Schizophrenic Patients is Associated with Higher Risks of Developing Bone Fractures and Refractures
Clinical Psychopharmacology and Neuroscience
2020 .01
-
조현병 약물치료의 최신 지견
대한의사협회지
2024 .02
이 논문의 저자 정보
최근 본 자료
댓글(0)
0