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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한치주과학회 Journal of Periodontal & Implant Science Journal of Periodontal & Implant Science 제33권 제2호
- 발행연도
- 2003.1
- 수록면
- 289 - 300 (12page)
이용수
초록· 키워드
The autogenous free gingival graft is the most predictable procedure currently used to increase the width of
the attached gingiva in periodontics. But the major disadvantage of the procedure is to create the multiple surgical
wounds at both a donor site and a recipient site. The other problem is the limited amount of available
graft material in oral cavity. Therefore, recent researches have been focused to develop the biomaterial to substitute
the autogenous gingival tissue. The purpose of this study was to evaluate the histologic healing after
grafting of bilayer artificial dermis, compared to the free gingival graft.
Four non-smoking subjects (mean age, 32.5 years) in systemically healthy state and good oral hygiene were
selected according to their particular needs for correction of mucogingival problems as suggested by
Nabers(1966). The recipient sites were prepared through the procedure for the free gingival graft and were
grouped according to the graft materials: Experimental group(n=5) - bilayer artificial dermis (Terudermis;
Terumo Co. Japan) and Control group(n=6) - free gingival graft with autogenous palatal mucosa. Biopsies
were harvested at 1, 2, 3 and 6 weeks postsurgery to evaluate histologically.
At the third week in the experimental group and at the second week of in the control group, the grafts has
been clinically stabilized on the recipient bed and the graft border has been blended into the surrounding tissue.
In the experimental group after 1 week of grafting, the epithelial migration from the adjacent tissue to graft
material was seen and after 3 weeks of grafting, the : nflmmation decreased, collagen layer of the artificial dermis
was lost and the basement membrane of epithelium was formed. After 6 weeks of grafting, both groups
demonstrated orthokeratinized epithelium and increased thickness of epithelial tissue and the rete peg formation,
similar to the adjacent tissue. Histologic evaluation revealed a biologic acceptance and incorporation of
the collagen layers of the graft tissue to the host tissue, without foreign body reaction.
In conclusion, a bilayer artificial dermis is essentially similar to autogeneous free gingival graft in the correction
of mucogingival problems, and has the advantages of decreased patient morbidity (no donor site) and
availability of abundant amounts of graft material when needed.
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