지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
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Objectives : This study was designed to test the effect of a warm environment and Bujaijung-tang on immune and lipid metabolism in rats.
Methods : The extract from Bujaijung-tang was made by the pharmacy department of Kyung-Hee oriental medical hospital. The animals were divided into four groups, by room or warm environment and Bujaijung-tang administration. Each group had 8 Sprague-Dawley Rats. We measured body temperature twice a week, body weight three times a week. After 3 weeks of experiment, serum lipid level, WBC, differential count, lymphocyte proliferation and immune cytokine concentration were measured.
Results :1. warm environment induced weight loss in rats.
2. warm environment induced a decrease of total cholesterol and low-density lipoprotein (LDL) cholesterol gain.
3. warm environment and Bujaijung-tang induced an increase of tumor necrosis factor (TNF)-α concentration.
Conclusions : The warm environment had a hyperlipidemia modulating effect. The warm environment and Bujaijung-tang had an immune modulating effect.
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참고문헌 (40)
참고문헌 신청
Bendtzen, K / 1988 / Interleukin 1, interleukin 6 and tumor necrosis factor in infection, inflammation and immunity / Immunol Letters 19 : 183 ~ 192
Hasday JD / 2000 / The role of fever in the infected host / Microbes and Infection 2 : 1891 ~ 1904
Invitti, C / 2002 / Obesity and low-grade systemic inflammation / Minerva Endocrinol 27 (3) : 209 ~ 241
Jhaveri KA / 2007 / Effect of environmental temperature on sleep, locomotor activity, core body temperature and immune responses of C57BL/6J mice / Brain Behav Immun 21 : 97
Kashio M / 2012 / Redox signal-mediated sensitization of transient receptor potential melastatin 2(TRPM2) to temperature affects macrophage functions / Proc Natl Acad Sci U
Hasday JD / 2000 / The role of fever in the infected host / Microbes and Infection 2 : 1891 ~ 1904
Invitti, C / 2002 / Obesity and low-grade systemic inflammation / Minerva Endocrinol 27 (3) : 209 ~ 241
Jhaveri KA / 2007 / Effect of environmental temperature on sleep, locomotor activity, core body temperature and immune responses of C57BL/6J mice / Brain Behav Immun 21 : 97
Kashio M / 2012 / Redox signal-mediated sensitization of transient receptor potential melastatin 2(TRPM2) to temperature affects macrophage functions / Proc Natl Acad Sci U
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