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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
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Objectives : This study was designed to test the effect of heating condition and Panax ginseng on body temperature, hematologicala changes, and immune response.
Methods : The extract from Panax ginseng was made by the pharmacy department of Kyung Hee Oriental Medical Hospital. The animals were divided into four groups; control, room temperature Panax ginseng (G), 28 ℃ heating, and 28 ℃ heating Panax ginseng (heating G). Each group has 8 Sprague-Dawley rats. We measured body weight & temperature twice a week. After 2 weeks of experiment, serum lipid level, WBC, differential count, lymphocyte proliferation and immune cytokine concentration were measured.
Results :1. Simultaneous application of heating condition and Panax ginseng induced decreased body weight and increased body temperature.
2. Simultaneous application of heating condition and Panax ginseng induced decreased AST, ALT and BUN.
3. Simultaneous application of heating condition and Panax ginseng tended to decrease TNF-α concentration, while application of room temperature and Panax ginseng tended to increase TNF-α concentration.
Conclusions : Simultaneous application of heating condition and Panax ginseng decreseas body weight, increases, body temperature and has a tendency to decrease TNF-α concentration.
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참고문헌 (35)
참고문헌 신청
Zelova H / 2013 / TNF-a signalling and inflammation: interactions between old acquaintances / Inflamm Res 62:641~651
Popa C / 2007 / The role of TNF-α in chronic inflammatory conditions, intermediary metabolism, and cardiovascular risk / J Lipid Res 48:751~762
Aggarwal BB / 2006 / Inflammation andcancer: how hot is the link / Biochem Pharmacol 11 : 1605 ~ 1621
Attele AS / 1999 / Ginseng Parmacology: multiple constituents and multiple actions / Biochem Pharmacol 58 : 1685 ~
Balkwill F / 2002 / Tumor necrosis factor or tumor promoting factor / Cytokine Growth Factor Rev 13 (2) : 135 ~ 141
Popa C / 2007 / The role of TNF-α in chronic inflammatory conditions, intermediary metabolism, and cardiovascular risk / J Lipid Res 48:751~762
Aggarwal BB / 2006 / Inflammation andcancer: how hot is the link / Biochem Pharmacol 11 : 1605 ~ 1621
Attele AS / 1999 / Ginseng Parmacology: multiple constituents and multiple actions / Biochem Pharmacol 58 : 1685 ~
Balkwill F / 2002 / Tumor necrosis factor or tumor promoting factor / Cytokine Growth Factor Rev 13 (2) : 135 ~ 141
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