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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2014.1
- 수록면
- 207 - 213 (7page)
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Mesenchymal stem cells (MSCs) are adult stem cells which are present in a variety of adult tissues and reside in essentially all post-natal organs and tissues. MSCs represent an important stem cell population with multi-potent capabilities which may have high utility for translational clinical applications. MSCs can be isolated from a number of adult tissues and differentiate into several mesenchymal lineages both in vitro and in vivo, such as bone, cartilage, adipose tissue, and muscle. Because of their capacities of differentiation, MSCs have emerged as a promising source for therapeutic applications in tissue engineering and regenerative medicine. In addition to their multi-lineage potential, MSCs have been shown to possess the unique ability to suppress immune response and modulate inflammation. MSCs can inhibit natural killer cell function, modulate dendritic cell maturation, and suppress the allogeneic T-cell response by alternating the cytokine secretion profile of dendritic cells and T-cells induced by an allogeneic immune reaction. Therefore, MSCs have been reported to have anti-inflammatory and immunomodulatory effects in a variety of chronic inflammatory diseases. In this article, I review recent experimental data and discuss about the application of MSCs in rhinologic fields.
Korean J Otorhinolaryngol-Head Neck Surg 2014;57(4):207-13
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참고문헌 (24)
참고문헌 신청
[학술지(정기간행물)
Bhagavati S / 2004 / Isolation and enrichment of skeletal muscle progenitor cells from mouse bone marrow / Biochem Biophys Res Commun 318 (1) : 119 ~ 124
Bosch P / 2000 / Osteoprogenitor cells within skeletal muscle / J Orthop Res 18 (6) : 933 ~ 944
Boulay ME / 2003 / The relationships between atopy, rhinitis and asthma: pathophysiological considerations / Curr Opin Allergy Clin Immunol 3 (1) : 51 ~ 55
De Bari C / 2001 / Multipotent mesenchymal stem cells from adult human synovial membrane / Arthritis Rheum 44 (8) : 1928 ~ 1942
Bhagavati S / 2004 / Isolation and enrichment of skeletal muscle progenitor cells from mouse bone marrow / Biochem Biophys Res Commun 318 (1) : 119 ~ 124
Bosch P / 2000 / Osteoprogenitor cells within skeletal muscle / J Orthop Res 18 (6) : 933 ~ 944
Boulay ME / 2003 / The relationships between atopy, rhinitis and asthma: pathophysiological considerations / Curr Opin Allergy Clin Immunol 3 (1) : 51 ~ 55
De Bari C / 2001 / Multipotent mesenchymal stem cells from adult human synovial membrane / Arthritis Rheum 44 (8) : 1928 ~ 1942
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