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Background and Objectives Sudden sensorineural hearing loss (S-SNHL) has been reportedto be associated with hypertension, diabetes mellitus, hyperlipidemia, and stroke inprevious studies. The purpose of this study was to confrm whether metabolic syndrome (MS)infuences the hearing outcome of S-SNHL in the Korean population. Subjects and Method We prospectively investigated the clinical variables of 231 cases ofS-SNHL from 2010 March to 2014 February. MS was defned according to the National CholesterolEducation Program Adult Treatment Panel III with Asian modifcations. We analyzedand compared the basic and clinical characteristics, the thresholds of pure tone audiometry(PTA), and the hearing outcomes of patients with MS (MS group) and without MS (NMSgroup). Results There were no signifcant differences in the basic characteristics and initial hearingthresholds between the MS and NMS groups; on the other hand, there were signifcant differencesin all of the clinical values of MS between the two groups. The average thresholds of finalPTA for the MS and NMS groups were 52.9±30.9 dB and 40.5±27.2 dB, respectively,with meaningful diversity (p<0.01). According to Siegel’s criteria, the recovery rate of theNMS group (95/159, 59.7%) was signifcantly higher than those of the MS group (29/72, 40.3%). The proportion of recovery within 5 days after starting the treatment was signifcantly higherof the NMS group (37/95, 39.0%) than those of the MS group (4/29, 13.8%) (p<0.01). Conclusion The hearing outcome of the NMS group was signifcantly better than those ofthe MS group.

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