중년 및 노인에서의 만성 폐쇄성 폐질환과 비용종 발생 감소의 상관성

이민구; 김시환; 양정환; 이주한; 최효근

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자료유형: 학술저널

저자정보: 이민구 김시환 양정환 이주한 최효근

저널정보: 대한이비인후과학회 대한이비인후-두경부외과학회지 대한이비인후과학회지 두경부외과학 제59권 제4호

발행연도: 2016.1

수록면: 287 - 292 (6page)

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이 논문의 연구 히스토리 (2)

2016

중년 및 노인에서의 만성 폐쇄성 폐질환과 비용종 발생 감소의 상관성

이민구 , 김시환 , 양정환 외 2명 대한이비인후-두경부외과학회지 2016.01 학술저널

2015

노인에서의 만성 폐쇄성 폐질환과 비용종 발생 감소의 상관성

이민구 의학과 2015.01 학위논문

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Background and Objectives Chronic obstructive pulmonary disease (COPD) is known to induce chronic rhinosinusitis (CRS). Nasal polyp, which is frequently found in patients with CRS, seems to have close relationship with COPD, but little is known about its relationship with COPD. In this study, we investigated the relationship between COPD and nasal polyp in middle aged and elderly CRS patients. Subjects and Method We analyzed the clinical data of 174 patients (age of over 50 years) with CRS. Patients were divided as COPD [forced expiratory volume (FEV1)/forced vital capacity (FVC)＜70%, n=30] and non-COPD group (FEV1/FVC≥70%, n=144) according to the pulmonary function test results. Binary logistic regression analysis was used to describe the relationships between clinically relevant factors related to nasal polyp. Results On logistic regression analysis, no significant relationship was found between age [adjusted odds ratio (AOR): 1.058, 95% confidence interval for the difference (CI)=0.995-1.126, p=0.073], sex AOR: 0.897, 95% CI=0.366-2.415, p=0.897), smoking (AOR: 0.434, 95% CI=0.154-1.219, p=0.113) and obesity (underweight AOR: 3.833, 95% CI=0.781-18.808, p= 0.098, overweight AOR: 5.169, 95% CI=0.996-26.814, p=0.051, obese AOR: 2.911, 95% CI= 0.335-25.329, p=0.333) with polyp. However, there was a negative correlation between COPD history and nasal polyp with statistical significance (AOR: 0.288, 95% CI=0.102-0.809, p=0.018). Conclusion Our findings suggest that patients with COPD are less likely to have nasal polyp than patients without COPD. Korean J Otorhinolaryngol-Head Neck Surg 2016;59(4):287-92

#Aged ㆍChronic obstructive pulmonary disease ㆍMiddle aged ㆍ Nasal polyps ㆍSinusitis.

참고문헌 (25)

참고문헌 신청

de Benedictis FM / 2001 / Rhinitis, sinusitis and asthma: one linked airway disease / Paediatr Respir Rev 2(4):358~364

Passalacqua G / 2001 / The nose-lung interaction in allergic rhinitis and asthma: united airways disease / Curr Opin Allergy Clin Immunol 1(1):7~13

Leynaert B / 2000 / Epidemiologic evidence for asthma and rhinitis comorbidity / J Allergy Clin Immunol 106(5 Suppl):S201~S205

Pfister R / 1994 / Screening for sinus disease in patients with asthma: a computed tomography-controlled comparison of A-mode ultrasonography and standard radiography / J Allergy Clin Immunol 94(5):804~809

Kim JS / 2008 / Nasal and sinus involvement in chronic obstructive pulmonary disease / Curr Opin Pulm Med 14(2):101~104

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