갑상선 전절제술 후 1시간에 측정한 혈청 부갑상선호르몬의 유용성

양윤수; 이은정; 소상수; 최동일; 공일승; 홍기환

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자료유형: 학술저널

저자정보: 양윤수 이은정 소상수 최동일 공일승 홍기환

저널정보: 대한이비인후과학회 대한이비인후-두경부외과학회지 대한이비인후과학회지 두경부외과학 제50권 제11호

발행연도: 2007.1

수록면: 1,012 - 1,016 (5page)

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연구주제

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연구방법

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연구결과

초록· 키워드

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Background and Objectives：Hypocalcemia is the most frequent complication following total thyroidectomy. This prospective study examines the predictive value of parathyroid hormone (PTH) levels measured 1 hour after surgery. Materials and Method：Twenty-four patients underwent total or near-total thyroidectomy for benign or malignant thyroid tumor in one year. Serum calcium and PTH levels were measured preoperatively and at 1 hour after surgery. Results：Al patients were clasified into three groups acording to hypocalcemic symptoms and postoperative serum calcium levels. A total of 6 (25% ) patients were found with hypocalcemia, as demonstrated by clinical and laboratory findings. PTH levels at 1 hour were below normal level (100% ) for 6 of the 6 symptomatic hypocalcemia patients, 5 (45% ) of the 11 biochemical hypocalcemia patients, and in 1 (14% ) of 7 normocalcemic patients (p= 0.002). The sensitivity and specificity of postoperative 1 hour PTH asesment to predict symp-tomatic hypocalcemia were 100% and 66%. The positive and negative predictive rate of postoperative 1 hour PTH assesment to predict symptomatic hypocalcemia were 50% and 10%. Conclusion：of transient hypocalcemia after bilateral thyroid surgery. Low PTH level at 1 hour after surgery is therefore a feasible predictor of postoperative symptomatic hypocalcemia and permanent hypoparathyroidism. (Korean J Otorhinolaryngol-Head Neck Surg 2007 ;50 :1012-6)

#갑상선 절제술·저칼슘혈증·부갑상선 호르몬. #Thyroidectomy· Hypocalcemia· Parathyoid hormone.

참고문헌 (9)

참고문헌 신청

/ / Murphy T. Risk factors for posthyoidectomy hypocalcemia. Surgery 1994 : 641 ~ 8

/ 1996 / The manage-ment of post-thyroidectomy hypocalcemia 75 (9) : 612 ~ 616

/ 1998 / Early postoperative calcium levels as predictors of hypocalcemia 108 (12) : 1829 ~ 1831

/ 2001 / Measurement of early serum calcium levels in predicting hypocalcemia after total/near total thy-roidectomy 44 (11) : 1183 ~ 1186

/ 2002 / Low parathyroid hormone levels after thryoid surgery: A feasible predictor of hypocalcemia 131 (5) : 515 ~ 520

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