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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한자기공명의과학회 Investigative Magnetic Resonance Imaging Investigative Magnetic Resonance Imaging 제21권 제3호
- 발행연도
- 2017.1
- 수록면
- 154 - 161 (8page)
이용수
초록· 키워드
오류제보하기
Purpose: To evaluate the diagnostic performance of diffusion-weighted steadystate free precession (DW-SSFP) in comparison to diffusion-weighted echo-planar imaging (DW-EPI) for differentiating the neoplastic and benign osteoporotic vertebral compression fractures.
Materials and Methods: The subjects were 40 patients with recent vertebral compression fractures but no history of vertebroplasty, spine operation, or chemotherapy. They had received 3-Tesla (T) spine magnetic resonance imaging (MRI), including both DW-SSFP and DW-EPI sequences. The 40 patients included 20 with neoplastic vertebral fracture and 20 with benign osteoporotic vertebral fracture.
In each fracture lesion, we obtained the signal intensity normalized by the signal intensity of normal bone marrow (SI norm) on DW-SSFP and the apparent diffusion coefficient (ADC) on DW-EPI. The correlation between the SI norm and the ADC in each lesion was analyzed using linear regression. The optimal cut-off values for the diagnosis of neoplastic fracture were determined in each sequence using Youden’s J statistics and receiver operating characteristic curve analyses.
Results: In the neoplastic fracture, the median SI norm on DW-SSFP was higher and the median ADC on DW-EPI was lower than the benign osteoporotic fracture (5.24 vs. 1.30, P = 0.032, and 0.86 vs. 1.48, P = 0.041, respectively). Inverse linear correlations were evident between SI norm and ADC in both neoplastic and benign osteoporotic fractures (r = -0.45 and -0.61, respectively). The optimal cut-off values for diagnosis of neoplastic fracture were SI norm of 3.0 in DW-SSFP with the sensitivity and specificity of 90.4% (95% confidence interval [CI]: 81.0-99.0) and 95.3% (95% CI: 90.0-100.0), respectively, and ADC of 1.3 in DW-EPI with the sensitivity and specificity of 90.5% (95% CI: 80.0-100.0) and 70.4% (95% CI: 60.0- 80.0), respectively.
Conclusion: In 3-T MRI, DW-SSFP has comparable sensitivity and specificity to DWEPI in differentiating the neoplastic vertebral fracture from the benign osteoporotic vertebral fracture.
목차
등록된 정보가 없습니다.
참고문헌 (16)
참고문헌 신청
/ / The Asian Audit: Epidemiology, costs and burden of osteoporosis in Asia 2009
An HS / 1995 / Can we distinguish between benign versus malignant compression fractures of the spine by magnetic resonance imaging? / Spine (Phila Pa 1976) 20 : 1776 ~ 1782
Baur A / 2001 / Diagnostic value of increased diffusion weighting of a steadystate free precession sequence for differentiating acute benign osteoporotic fractures from path
Bhugaloo A / 2006 / Diffusion weighted MR imaging in acute vertebral compression fractures:differentiation between malignant and benign causes / Biomed Imaging Interv J 2 : e
Biffar A / 2011 / Quantitative analysis of the diffusion-weighted steadystate free precession signal in vertebral bone marrow lesions / Invest Radiol 46 : 601 ~ 609
An HS / 1995 / Can we distinguish between benign versus malignant compression fractures of the spine by magnetic resonance imaging? / Spine (Phila Pa 1976) 20 : 1776 ~ 1782
Baur A / 2001 / Diagnostic value of increased diffusion weighting of a steadystate free precession sequence for differentiating acute benign osteoporotic fractures from path
Bhugaloo A / 2006 / Diffusion weighted MR imaging in acute vertebral compression fractures:differentiation between malignant and benign causes / Biomed Imaging Interv J 2 : e
Biffar A / 2011 / Quantitative analysis of the diffusion-weighted steadystate free precession signal in vertebral bone marrow lesions / Invest Radiol 46 : 601 ~ 609
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