지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2017.1
- 수록면
- 47 - 52 (6page)
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초록· 키워드
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Purpose: Renal ultrasonography has been widely used in children with renal disease. However, the relationship of renal echogenicity with renal pathology and function in children is not well known.
Method: Ultrasound examination was performed in 75 patients undergoing renal biopsy for suspected renal disease in Konkuk University Medical Center from August 2005 to November 2015. We compared renal echogenicity to pathologic findings and renal function. Renal echogenicity was scored as 0 to 2 by comparing adjacent liver echogenicity. Three histologic characteristics were evaluated: glomerular changes, interstitial infiltration or fibrosis, and tubular atrophy. These were graded as 0 to 3, according to increasing severity. Laboratory results included urine albumin excretion and estimated glomerular filtration rate (eGFR).
Results: Among pathologic findings, renal echogenicity revealed a positive correlation with interstitial infiltration or fibrosis (r=0.259, P =0.025), and with tubular atrophy (r=0.268, P=0.02). Renal echogenicity and glomerular changes were not correlated . Renal echogenicity showed a positive correlation with microalbuminuria (r=0.283, P =0.014), but a negative correlation with eGFR (r=-0.352, P =0.002).
Conclusion: Increased renal echogenicity suggested severe interstitial infiltration or fibrosis and tubular atrophy among the pathologic findings. Moreover, increased echogenicity is correlated with increased urine albumin excretion and decreased eGFR. Echogenicity on ultrasonography is useful for determining the status of renal pathology and function.
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참고문헌 (18)
참고문헌 신청
Brenbridge AN / 1986 / Increased renal cortical echogenicity in pediatric renal disease: histopathologic correlations / J Clin Ultrasound 14 (8) : 595 ~ 600
Buturovic-Ponikvar J / 2003 / Ultrasonography in chronic renal failure / Eur J Radiol 46 (2) : 115 ~ 122
Chi T / 2006 / Increased echogenicity as a predictor of poor renal function in children with grade 3 to 4 hydronephrosis / J Urol 175 (5) : 1898 ~ 1901
Ghasemi A / 2015 / Pediatric reference values for serum creatinine and estimated glomerular filtration rate in Iranians: Tehran Lipid and Glucose Study / Arch Iran Med 18 (1
Han BK / 1985 / Sonographic measurements and appearance of normal kidneys in children / AJR Am J Roentgenol 145 (3) : 611 ~
Buturovic-Ponikvar J / 2003 / Ultrasonography in chronic renal failure / Eur J Radiol 46 (2) : 115 ~ 122
Chi T / 2006 / Increased echogenicity as a predictor of poor renal function in children with grade 3 to 4 hydronephrosis / J Urol 175 (5) : 1898 ~ 1901
Ghasemi A / 2015 / Pediatric reference values for serum creatinine and estimated glomerular filtration rate in Iranians: Tehran Lipid and Glucose Study / Arch Iran Med 18 (1
Han BK / 1985 / Sonographic measurements and appearance of normal kidneys in children / AJR Am J Roentgenol 145 (3) : 611 ~
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