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자료유형
학술저널
저자정보
저널정보
대한간학회 Clinical and Molecular Hepatology Clinical and Molecular Hepatology 제20권 제1호
발행연도
2014.1
수록면
71 - 75 (5page)

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An 84-year-old man was admitted to our hospital with fever, jaundice, and itching. He had been diagnosed previouslywith chronic renal failure and diabetes, and had been taking allopurinol medication for 2 months. A physical examinationrevealed that he had a fever (38.8ºC), jaundice, and a generalized maculopapular rash. Azotemia, eosinophilia, atypicallymphocytosis, elevation of liver enzymes, and hyperbilirubinemia were detected by blood analysis. Magnetic resonancecholangiography revealed multiple cysts similar to choledochal cysts in the liver along the biliary tree. Obstructivejaundice was suspected clinically, and so an endoscopic ultrasound examination was performed, which ruled out adiagnosis of obstructive jaundice. The patient was diagnosed with DRESS (Drug Rash with Eosinophilia and SystemicSymptoms) syndrome due to allopurinol. Allopurinol treatment was stopped and steroid treatment was started. Thepatient died from cardiac arrest on day 15 following admission.

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