지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2015.1
- 수록면
- 1 - 7 (7page)
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초록· 키워드
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Introduction: Serum uric acid (UA) has been known to have a positive association with blood pressure (BP).
However, the relationship between serum UA and BP in different age groups is unclear.
Methods: A total of 45,098 Koreans who underwent health examinations at Korea Association of Health Promotion with no history of taking drugs related with UA and/or BP were analyzed for determining the relationship between serum UA and BP.
Results: In men <40, serum UA was significantly associated with systolic (β = 0.25, p = 0.002) and diastolic BP (β = 0.41, p < 0.001) after adjustment for age, diabetes, dyslipidemia, body mass index, and estimated glomerular filtration rate.
Men between ages 40 and 59 showed similar results regarding diastolic BP. The association between serum UA and BP was stronger in women <40 (β = 0.54, p < 0.001 for systolic BP; β = 0.65, p < 0.001 for diastolic BP) and in between 40 and 59 (β = 0.51, p < 0.001 for diastolic BP). The association was not significant in men and women ≥60. The odds ratios (ORs) of hyperuricemia for hypertension were 1.25 (95% confidence interval [CI], 1.08 to 1.45; p = 0.003) and 1.33 (95% CI, 1.11 to 1.60; p = 0.002) in men <40 and in between 40 and 59, respectively, in the multivariate analysis. The OR was 2.60 (95% CI, 1.37 to 4.94; p = 0.0034) in women <40. The relationship between hyperuricemia and hypertension was not significant in other age/gender groups.
Discussion: In contrast to the elderly of 60 and over, the non-elderly showed significant associations between serum UA and BP.
목차
등록된 정보가 없습니다.
참고문헌 (24)
참고문헌 신청
Bengtsson C. / 1988 / Hyperuricaemia and risk of cardiovascular disease and overall death : a 12-year follow-up of participants in the population study of women in Gothenbur
Brand FN. / 1985 / Hyperuricemia as a risk factor of coronary heart disease : the Framingham study / Am J Epidemiol 121 : 11 ~ 18
Coresh J. / 2001 / Prevalence of high blood pressure and elevated serum creatinine level in the United States : findings from the third National Health and Nutrition Examinat
Culleton BF. / 1999 / Serum uric acid and risk for cardiovascular disease and death : the Framingham heart study / Ann Intern Med 131 : 7 ~ 13
Feig DI. / 2003 / Hyperuricemia in childhood primary hypertension / Hypertension 42 : 247 ~ 252
Brand FN. / 1985 / Hyperuricemia as a risk factor of coronary heart disease : the Framingham study / Am J Epidemiol 121 : 11 ~ 18
Coresh J. / 2001 / Prevalence of high blood pressure and elevated serum creatinine level in the United States : findings from the third National Health and Nutrition Examinat
Culleton BF. / 1999 / Serum uric acid and risk for cardiovascular disease and death : the Framingham heart study / Ann Intern Med 131 : 7 ~ 13
Feig DI. / 2003 / Hyperuricemia in childhood primary hypertension / Hypertension 42 : 247 ~ 252
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