지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2012.1
- 수록면
- 29 - 37 (9page)
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Background:Wide pulse pressure associates with atherosclerosis, but it is unclear whether pulse pressure within a relatively normal range is associated with atherosclerosis in younger populations. The aim of this study was to investigate the association between pulse pressure and the carotid intima-media thickness (IMT) in healthy adolescents. Methods: Study participants included 250 (129 males and 121 females) adolescents who were 17 to 19 years old and in the third grade of a high school in Jangseong, Korea between November 20 and December 1, 2009. Pulse pressure was determined as the difference between systolic blood pressure and diastolic blood pressure which were measured with an oscillometric sphygmomanometer. IMT values were ultrasonographically measured at right and left common carotid arteries, and average of the mean IMT at each artery was used for analysis. Results: There was a significant correlation between pulse pressure and carotid IMT before (Pearson coefficient r = 0.2037, p = 0.001) and after (r = 0.1479, p = 0.020) adjustment for sex. When adjusted for sex, age, waist circumference,fasting blood glucose, and total/high-density lipoprotein cholesterol ratio, 10 mm Hg increase in pulse pressure was associated with increase of IMT in total (β = 10.9 ㎛, p = 0.003), in males (β = 17.3 ㎛, p < 0.001), but not in females (β = 3.609 ㎛, p =0.518). Conclusions: This study suggests that higher pulse pressure may be associated with increased carotid IMT even in healthy male adolescents.
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참고문헌 (20)
참고문헌 신청
/ 2004 / National High Blood Pressure Education Program Working Group on High Blood Pressure in Children and Adolescents. The fourth report on the diagnosis, evaluation, and
Bilginer Y / 2007 / Carotid intima-media thickness in children and young adults with renal transplant: Internal carotid artery vs. common carotid artery / Pediatr Transplant
Fang J / 1995 / Measures of blood pressure and myocardial infarction in treated hypertensive patients / J Hypertens 13 : 413 ~ 419
Fang J / 2010 / Carotid Intima-media thickness in childhood and adolescent obesity relations to abdominal obesity, high triglyceride level and insulin resistance / Int J Med
Jourdan C / 2005 / Normative values for intima-media thickness and distensibility of large arteries in healthy adolescents / J Hypertens 23 : 1707 ~ 1715
Bilginer Y / 2007 / Carotid intima-media thickness in children and young adults with renal transplant: Internal carotid artery vs. common carotid artery / Pediatr Transplant
Fang J / 1995 / Measures of blood pressure and myocardial infarction in treated hypertensive patients / J Hypertens 13 : 413 ~ 419
Fang J / 2010 / Carotid Intima-media thickness in childhood and adolescent obesity relations to abdominal obesity, high triglyceride level and insulin resistance / Int J Med
Jourdan C / 2005 / Normative values for intima-media thickness and distensibility of large arteries in healthy adolescents / J Hypertens 23 : 1707 ~ 1715
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