지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2016.1
- 수록면
- 69 - 74 (6page)
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초록· 키워드
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Purpose: We aimed to assess whether nerve-sparing radical prostatectomy (nsRP) is associated with improved recovery of urinary continence compared to non–nerve-sparing radical prostatectomy (nnsRP) in patients with localized prostate cancer and preoperative erectile dysfunction.
Methods: A total of 360 patients with organ-confined prostate cancer and an International Index of Erectile Function score of less than 17 were treated with nsRP or nnsRP in Seoul St. Mary’s Hospital. Patients who received neoadjuvant or adjuvant androgen deprivation therapy or had a history of prostate-related surgery were excluded. Recovery of urinary continence was assessed at 0, 1, 3, 6, and 12 months. Postoperative recovery of continence was defined as zero pad usage. The association between nerve-sparing status and urinary continence was assessed by using univariate and multivariate Cox regression analyses after controlling for known predictive factors.
Results: Urinary continence recovered in 279 patients (77.5%) within the mean follow-up period of 22.5 months (range, 6–123 months). Recovery of urinary continence was reported in 74.6% and 86.4% of patients after nnsRP and nsRP, respectively, at 12 months (P=0.022). All groups had comparable perioperative criteria and had no significant preoperative morbidities.
Age, American Society of Anesthesiologists score, and nerve-sparing status were significantly associated with recovery of urinary continence on univariate analysis. On multivariate analysis, age (hazard ratio [HR], 1.254; 95% confidence interval [CI], 1.002–1.478; P=0.026) and nerve-sparing status (HR, 0.713; 95% CI, 0.548–0.929; P=0.012) were independently associated with recovery of urinary continence.
Conclusions: nsRP, as compared to nnsRP, improves recovery rates of urinary incontinence and decreases surgical morbidity without compromising pathologic outcomes.
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등록된 정보가 없습니다.
참고문헌 (21)
참고문헌 신청
정규원 / 2014 / Cancer Statistics in Korea: Incidence, Mortality, Survival, and Prevalence in 2011 / Cancer Research and Treatment 46(2):109~123
Finley DS / 2009 / Hypothermic robotic radical prostatectomy: impact on continence / J Endourol 23:1443~1450
Lei Y / 2011 / Athermal division and selective suture ligation of the dorsal vein complex during robot-assisted laparoscopic radical prostatectomy:description of technique and outcomes / Eur Urol 59:235~243
Joshi N / 2010 / Impact of posterior musculofascial reconstruction on early continence after robot-assisted laparoscopic radical prostatectomy: results of a prospective parallel group trial / Eur Urol 58:84~89
Ficarra V / 2012 / Systematic review and meta-analysis of studies reporting urinary continence recovery after robot-assisted radical prostatectomy / Eur Urol 62:405~417
Finley DS / 2009 / Hypothermic robotic radical prostatectomy: impact on continence / J Endourol 23:1443~1450
Lei Y / 2011 / Athermal division and selective suture ligation of the dorsal vein complex during robot-assisted laparoscopic radical prostatectomy:description of technique and outcomes / Eur Urol 59:235~243
Joshi N / 2010 / Impact of posterior musculofascial reconstruction on early continence after robot-assisted laparoscopic radical prostatectomy: results of a prospective parallel group trial / Eur Urol 58:84~89
Ficarra V / 2012 / Systematic review and meta-analysis of studies reporting urinary continence recovery after robot-assisted radical prostatectomy / Eur Urol 62:405~417
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