지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2011.1
- 수록면
- 45 - 50 (6page)
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초록· 키워드
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Purpose: We report herein 119 patients with pheochromocytoma at our institute over the last 23 years. Materials and Methods: Between 1986 and 2009, 119 patients were diagnosed with pheochromocytoma at our institute. We reviewed the medical records of these patients. Results: Of 119 patients, 45 were male and 74 were female, and mean age was 43.83 ± 13.49 years. Forty-three patients (36.1%) were diagnosed incidentally, and 8 patients (6.7%) were found to have familial pheochromocytoma. The mean dimension of the tumors was 5.89 ± 3.18 cm. 4 patients had bilateral tumors; three of these patients were found to have familial pheochromocytoma and 1 patient was diagnosed with malignant pheochromocytoma.
A total of eight patients (6.7%) were found to have malignant pheochromocytoma.
In 1 patient, metastasis to a lymph node was found at the time of diagnosis.
Metastases were found at a mean of 49 ± 25.83 (6-75) months after surgery in the other seven patients. 6 patients died of malignant pheochromocytoma at a mean of 31 ± 28.71 months (1-81) after diagnosis, and the other 2 patients survived for 15 and 24 months, respectively. Conclusion: Approximately 35% of patients with pheochromocytoma are diagnosed incidentally, and the number of detected cases is increasing. Although familial pheochromocytoma was found only in 6.7% of the patients, genetic testing should be considered in all patients, especially in patients with a family history, young age, or multifocal, bilateral, extra-adrenal, or malignant tumors. Given that malignant pheochromocytomas are frequently diagnosed during the follow-up period, long-term follow-up is necessary to confirm the absence of recurrence or metastasis.
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참고문헌 (26)
참고문헌 신청
[학술지(
Adler JT / 2008 / Pheochromocytoma: current approaches and future directions / Oncologist 13 : 779 ~ 793
Brouwers FM / 2006 / High frequency of SDHB germline mutations in patients with malignant catecholamine-producing paragangliomas: implications for genetic testing / J Clin E
Chrisoulidou A / 2007 / The diagnosis and management of malignant phaeochromocytoma and paraganglioma / Endocr Relat Cancer 14 : 569 ~ 585
Favia G / 1998 / Pheochromocytoma, a rare cause of hypertension: long-term follow-up of 55 surgically treated patients / World J Surg 22 : 689 ~ 693
Adler JT / 2008 / Pheochromocytoma: current approaches and future directions / Oncologist 13 : 779 ~ 793
Brouwers FM / 2006 / High frequency of SDHB germline mutations in patients with malignant catecholamine-producing paragangliomas: implications for genetic testing / J Clin E
Chrisoulidou A / 2007 / The diagnosis and management of malignant phaeochromocytoma and paraganglioma / Endocr Relat Cancer 14 : 569 ~ 585
Favia G / 1998 / Pheochromocytoma, a rare cause of hypertension: long-term follow-up of 55 surgically treated patients / World J Surg 22 : 689 ~ 693
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