지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2011.1
- 수록면
- 393 - 400 (8page)
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초록· 키워드
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Preparation of high quality allergen extracts is essential for the diagnosis and immunotherapy of allergic disorders. Standardization of allergen extracts concerns determination of the allergen unit, development of reference material and measurement of the overall IgE binding capacity of an allergen extract. Recently, quantification of individual allergens has been the main focus of allergen standardization because the allergenicity of most allergen extracts is known to be mainly dependent on the content of a small number of allergen molecules. Therefore, characterization of major allergens will facilitate the standardization of allergens. In this article, we review the current state of allergen standardization. In addition, we briefly summarize the components of allergen extracts that should be under control for the optimization of allergen standardization, since its adjuvant-like activities could play an important role in allergic reactions even though the molecule itself does not bind to the IgE antibodies from subjects.
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참고문헌 (25)
참고문헌 신청
Brunetto B / 2010 / Characterization and comparison of commercially available mite extracts for in vivo diagnosis / Allergy 65 : 184 ~ 190
Burazer L / 2011 / Impact of Dermatophagoides pteronyssinus mite body raw material on house dust mite allergy diagnosis in a Serbian population / Med Vet Entomol 25 : 77 ~ 83
Creticos PS / 2006 / Immunotherapy with a ragweed-toll-like receptor 9 agonist vaccine for allergic rhinitis / N Engl J Med 355 : 1445 ~ 1455
Dreborg S / 1992 / Precision of biological standardization of allergenic preparations / Allergy 47 : 291 ~ 294
Dreborg S / 1992 / The major allergen content of allergenic preparations reflect their biological activity / Allergy 47 : 418 ~ 423
Burazer L / 2011 / Impact of Dermatophagoides pteronyssinus mite body raw material on house dust mite allergy diagnosis in a Serbian population / Med Vet Entomol 25 : 77 ~ 83
Creticos PS / 2006 / Immunotherapy with a ragweed-toll-like receptor 9 agonist vaccine for allergic rhinitis / N Engl J Med 355 : 1445 ~ 1455
Dreborg S / 1992 / Precision of biological standardization of allergenic preparations / Allergy 47 : 291 ~ 294
Dreborg S / 1992 / The major allergen content of allergenic preparations reflect their biological activity / Allergy 47 : 418 ~ 423
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