지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2007.1
- 수록면
- 678 - 683 (6page)
이용수
초록· 키워드
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Purpose: This study aimed to evaluate the cancer detection rate in a Korean population with prostate-specific antigen (PSA) levels greater than or equal to 20.0ng/mL. Materials and Methods: A total of 174 men 50 to 79 years old (median 69) included in the study. The median prostate volume of the patients was 44.8mL (range 14.1 to 210.0) and their serum PSA ranged from 20.0 to 9725.0ng/mL (median 44.8). Results: Of 174 men 141 (81.0%) were diagnosed with prostate cancer on initial biopsy. In the total number of patients, the positive predictive value (PPV) was 62.9% for PSA 20 to 29.9, 72.7% for PSA 30 to 39.9 and 100% for PSA 40 to 49.9 ng/mL. In patients with an abnormal digital rectal examination (DRE), the values for these PSA ranges increased to 89.5%, 91.7% and 100%, respectively. The PPV was 81.0% for PSA cutoff of 20, 89.2% for a cutoff of 30, 95.4% for a cutoff of 40, and 94.7% for a cutoff of 50 ng/mL. In conjunction with an abnormal DRE, the values for these PSA cutoffs increased to 95.9%, 98.1%, 100%, and 100%, respectively. Conclusion: Our data suggest the ability to predict the presence of prostate cancer reliably on initial biopsy when PSA threshold is greater than or equal to 50ng/mL. This PSA threshold may be lowered to 40ng/mL in the presence of an abnormal DRE. In Korean men with high PSA, the detection rate of prostate cancer on biopsy appears to be comparable to that for American men.
목차
등록된 정보가 없습니다.
참고문헌 (18)
참고문헌 신청
Carter HB / 2004 / Prostate cancers in men with low PSA levels-must we find them? 350 : 292 ~ 294
Cooner WH / jurol1990;143 / Prostate cancer detection in a clinical urological practice by ultrasonography : 1146 ~ 52
Egawa S / 1998 / Results of transrectal ultrasound- guided biopsies and clinical significance of Japanese prostate cancer 28 : 666 ~ 672
Gerstenbluth RE / 2002 / The accuracy of the increased prostate specific antigen level (greater than or equal to 20ng./ ml.) in predicting prostate cancer: is biopsy always r
Haas GP / jurol1993;150 / The frequency of carcinoma and intraepithelial neoplasia of the prostate in young male patients : 379 ~ 85
Cooner WH / jurol1990;143 / Prostate cancer detection in a clinical urological practice by ultrasonography : 1146 ~ 52
Egawa S / 1998 / Results of transrectal ultrasound- guided biopsies and clinical significance of Japanese prostate cancer 28 : 666 ~ 672
Gerstenbluth RE / 2002 / The accuracy of the increased prostate specific antigen level (greater than or equal to 20ng./ ml.) in predicting prostate cancer: is biopsy always r
Haas GP / jurol1993;150 / The frequency of carcinoma and intraepithelial neoplasia of the prostate in young male patients : 379 ~ 85
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Changes in Serum Prostate-Specific Antigen after Treatment with Antibiotics in Patients with Lower Urinary Tract Symptoms/Benign Prostatic Hyperplasia with Prostatitis
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전립선암 진단에 있어서 Architect 총 PSA 화학발광면역검사법의 유용성 평가
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Practice Patterns of Korean Urologists for Screening and Managing Prostate Cancer according to PSA Level
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Exponential Rise in Prostate-Specific Antigen (PSA) during Anti-Androgen Withdrawal Predicts PSA Flare after Docetaxel Chemotherapy in Patients with Castration-Resistant Prostate Cancer
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Study on Interpretation of Quantitative Results of Prostate-specific Antigen Using Information Theory
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Impact of PSA and DRE on Histologic Findings at Prostate Biopsy in Turkish Men Over 75 Years of Age
Asian Pacific journal of cancer prevention : APJCP
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재발성 전립선암 환자에서 낮은 전립성특이항원을 보인폐전이 1예
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Head to Head Comparison of the Chun Nomogram, Percentage Free PSA and Primary Circulating Prostate Cells to Predict the Presence of Prostate Cancer at Repeat Biopsy
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