지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2013.1
- 수록면
- 1,273 - 1,281 (9page)
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초록· 키워드
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Purpose: Opioid-based intravenous patient-controlled analgesia (IV PCA) is popular method of postoperative pain control, but many patients suffer from IV PCA-related postoperative nausea and vomiting (PONV). In this retrospective observational study, we have determined independent predictors of IV PCA-related PONV and predictive values of the Apfel’s simplified risk score in pursuance of identifying high-risk patients. Materials and Methods: We analyzed 7000 patients who received IV PCA with background infusion after elective surgery. Patients who maintained IV PCA for a postoperative period of 48 hr (completion group, n=6128) were compared with those who have discontinued IV PCA within 48 hr of surgery due to intractable PONV (cessation group, n=872). Patients, anesthetics, and surgical factors known for predicting PONV were evaluated by logistic regression analysis to identify independent predictors of IV PCA related intractable PONV. Results:In a stepwise multivariate analysis, weight, background infusion dose of fentanyl, addition of ketolorac to PCA, duration of anesthesia, general anesthesia, head and neck surgery, and Apfel’s simplified risk score were revealed as independent risk factors for intractable PONV followed by the cessation of IV PCA. In addition,Apfel’s simplified risk score, which demonstrated the highest odds ratio among the predictors, was strongly correlated with the cessation rate of IV PCA. Conclusion: Multimodal prophylactic antiemetic strategies and dose reduction of opioids may be considered as strategies for the prevention of PONV with the use of IV PCA, especially in patients with high Apfel’s simplified risk scores.
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참고문헌 (23)
참고문헌 신청
Apfel CC / 1999 / A simplified risk score for predicting postoperative nausea and vomiting: conclusions from cross-validations between two centers / Anesthesiology 91 : 693
Apfel CC / 2001 / What can be expected from risk scores for predicting postoperative nausea and vomiting? / Br J Anaesth 86 : 822 ~ 827
Apfel CC / 2002 / Comparison of predictive models for postoperative nausea and vomiting / Br J Anaesth 88 : 234 ~ 240
Apfel CC / 2002 / Volatile anaesthetics may be the main cause of early but not delayed postoperative vomiting: a randomized controlled trial of factorial design / Br J Anaes
Ballantyne JC / 1993 / Postoperative patient-controlled analgesia: meta-analyses of initial randomized control trials / J Clin Anesth 5 : 182 ~ 193
Apfel CC / 2001 / What can be expected from risk scores for predicting postoperative nausea and vomiting? / Br J Anaesth 86 : 822 ~ 827
Apfel CC / 2002 / Comparison of predictive models for postoperative nausea and vomiting / Br J Anaesth 88 : 234 ~ 240
Apfel CC / 2002 / Volatile anaesthetics may be the main cause of early but not delayed postoperative vomiting: a randomized controlled trial of factorial design / Br J Anaes
Ballantyne JC / 1993 / Postoperative patient-controlled analgesia: meta-analyses of initial randomized control trials / J Clin Anesth 5 : 182 ~ 193
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