지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2017.1
- 수록면
- 123 - 130 (8page)
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초록· 키워드
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Purpose: Patients with superficial middle cerebral artery (MCA) territory infarction may have concomitant lenticulostriate artery (LSA) territory infarction. We investigated the mechanisms thereof and the outcomes of patients with superficial MCA territory infarction according to the presence or absence of LSA involvement.
Materials and Methods: Consecutive patients with first-ever infarction in the unilateral superficial MCA territory were included in this study. They were divided into the superficial MCA only (SM) group and the superficial MCA plus LSA (SM+L) group.
Results: Of the 398 patients, 84 patients (21.1%) had LSA involvement (SM+L group). The SM+L group more frequently had significantstenosis of the proximal MCA or carotid artery and high-risk cardioembolic sources. Stroke severity and outcomes were remarkably different between the groups. The SM+L group showed more severe neurologic deficits (National Institute of Health Stroke Scale score 10.8±7.1 vs. 4.0±5.0, p<0.001) and larger infarct in the superficial MCA territory (40.8±62.6 cm3 vs. 10.8±21.8 cm3, p<0.001) than the SM group. A poor functional outcome (mRS >2) at 3 months was more common in the SM+L group (64.3% vs. 15.9%, p<0.001). During a mean follow-up of 26 months, 67 patients died. All-cause (hazard ratio, 2.246) and stroke (hazard ratio,9.193) mortalities were higher in the SM+L group than the SM group. In multivariate analyses, LSA involvement was an independentpredictor of poor functional outcomes and stroke mortality.
Conclusion: LSA territory involvement is predictive of poor long-term outcomes in patients with superficial MCA territory infarction.
목차
등록된 정보가 없습니다.
참고문헌 (29)
참고문헌 신청
Mohr JP / 2011 / Stroke: pathophysiology, diagnosis, and management / Elsevier Saunders :384~424
강지훈 / 2014 / Symptomatic steno-occlusion in patients with acute cerebral infarction: Prevalence, distribution, and functional outcome / 대한뇌졸중학회지 16(1):36~43
Bang OY / 2005 / Specific DWI lesion patterns predict prognosis after acute ischaemic stroke within the MCA territory / J Neurol Neurosurg Psychiatry 76:1222~1228
Berman SA / 1984 / Correlation of CT cerebral vascular territories with function: 3. Middle cerebral artery / AJR Am J Roentgenol 142:1035~1040
Moulin DE / 1985 / Prognosis in middle cerebral artery occlusion / Stroke 16:282~284
강지훈 / 2014 / Symptomatic steno-occlusion in patients with acute cerebral infarction: Prevalence, distribution, and functional outcome / 대한뇌졸중학회지 16(1):36~43
Bang OY / 2005 / Specific DWI lesion patterns predict prognosis after acute ischaemic stroke within the MCA territory / J Neurol Neurosurg Psychiatry 76:1222~1228
Berman SA / 1984 / Correlation of CT cerebral vascular territories with function: 3. Middle cerebral artery / AJR Am J Roentgenol 142:1035~1040
Moulin DE / 1985 / Prognosis in middle cerebral artery occlusion / Stroke 16:282~284
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