지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2017.1
- 수록면
- 1,152 - 1,159 (8page)
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초록· 키워드
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Purpose: We explored whether a gender difference was evident in terms of the associations of snoring with hemoglobin A1c (HbA1c) and homeostatic model assessment-insulin resistance (HOMA-IR) levels in a healthy population without type 2 diabetes mellitus (DM).
Materials and Methods: We analyzed 2706 males and 4080 females who participated in the baseline survey of the Namwon Study. In terms of self-reported snoring frequency, participants were classified as non-snorers or occasional (1.3 days/week), frequent (4.6 days/week), or constant (7 days/week) snorers. Participants with DM, defined as a fasting blood glucose level ≥126 mg/dL and/or use of insulin or hypoglycemic medication, were excluded from the analysis.
Results: In females, the fully adjusted mean (95% confidence interval) HbA1c levels in non-snorers and in occasional, frequent, and constant snorers were 5.53% (5.47.5.59%), 5.53% (5.47.5.59%), 5.57% (5.49.5.64%), and 5.57% (5.51.5.64%), respectively, reflectinga dose-response relationship (p trend=0.004). Compared with female non-snorers, the risk of an elevated HbA1c level (top quintile, ≥5.9%) in constant snorers remained significant (odds ratio 1.30, 95% confidence interval 1.02.1.66) after full adjustment. In addition, in females, a significant linear trend in HbA1c level odds ratio by increased snoring frequency was apparent (p trend= 0.019 in model 3). In contrast, no significant association between snoring frequency and HbA1c level was identified in males. No significantassociation between snoring frequency and HOMA-IR was detected in either gender.
Conclusion: We discovered a gender-specific association between snoring and HbA1c level in a healthy, community-dwelling populationfree of DM.
목차
등록된 정보가 없습니다.
참고문헌 (24)
참고문헌 신청
Al-Delaimy WK / 2002 / Snoring as a risk factor for type II diabetes mellitus: a prospective study / Am J Epidemiol 155 : 387 ~ 393
Alam I / 2007 / Obesity, metabolic syndrome and sleep apnoea: all pro-inflammatory states / Obes Rev 8 : 119 ~ 127
Bennett CM / 2007 / HbA(1c) as a screening tool for detection of type 2 diabetes: a systematic review / Diabet Med 24 : 333 ~ 343
Drager LF / 2010 / Metabolic consequences of intermittent hypoxia: relevance to obstructive sleep apnea / Best Pract Res Clin Endocrinol Metab 24 : 843 ~ 851
Elley CR / 2008 / Glycated haemoglobin and cardiovascular outcomes in people with Type 2 diabetes: a large prospective cohort study / Diabet Med 25 : 1295 ~ 1301
Alam I / 2007 / Obesity, metabolic syndrome and sleep apnoea: all pro-inflammatory states / Obes Rev 8 : 119 ~ 127
Bennett CM / 2007 / HbA(1c) as a screening tool for detection of type 2 diabetes: a systematic review / Diabet Med 24 : 333 ~ 343
Drager LF / 2010 / Metabolic consequences of intermittent hypoxia: relevance to obstructive sleep apnea / Best Pract Res Clin Endocrinol Metab 24 : 843 ~ 851
Elley CR / 2008 / Glycated haemoglobin and cardiovascular outcomes in people with Type 2 diabetes: a large prospective cohort study / Diabet Med 25 : 1295 ~ 1301
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