지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2015.1
- 수록면
- 332 - 339 (8page)
이용수
초록· 키워드
오류제보하기
Purpose: Although the polymorphisms of erythrocyte complement receptor type 1 (CR1) in patients with malaria have been extensively studied, a question of whether the polymorphisms of CR1 are associated with severe malaria remains controversial.
Furthermore, no study has examined the association of CR1 polymorphisms with malaria in Chinese population. Therefore, we investigated the relationship of CR1 gene polymorphism and malaria in Chinese population. Materials and Methods:We analyzed polymorphisms of CR1 gene rs2274567 G/A, rs4844600 G/A, and rs2296160 C/T in 509 patients with malaria and 503 controls, using the Taqmangenotyping assay and PCR-direct sequencing. Results: There were no significantdifferences in the genotype, allele and haplotype frequencies of CR1 gene rs2274567 G/A, rs4844600 G/A, and rs2296160 C/T polymorphisms between patientswith malaria and controls. Furthermore, there was no association of polymorphismsin the CR1 gene with the severity of malaria in Chinese population. Conclusion:These findings suggest that CR1 gene rs2274567 G/A, rs4844600 G/A, and rs2296160 C/T polymorphisms may not be involved in susceptibility to malariain Chinese population.
목차
등록된 정보가 없습니다.
참고문헌 (23)
참고문헌 신청
Awandare GA / 2011 / Plasmodium falciparum field isolates use complement receptor 1 (CR1) as a receptor for invasion of erythrocytes / Mol Biochem Parasitol 177 : 57 ~ 60
Cockburn IA / 2004 / A human complement receptor 1 polymorphism that reduces Plasmodium falciparum rosetting confers protection against severe malaria / Proc Natl Acad Sci U
Cockburn IA / 2006 / Erythrocyte complement receptor 1 (CR1) expression level is not associated with polymorphisms in the promoter or 3’ untranslated regions of the CR1 gen
Fernandez-Arias C / 2013 / Malaria inhibits surface expression of complement receptor 1 in monocytes/macrophages, causing decreased immune complex internalization / J Immuno
Lapin ZJ / 2012 / Near-field quantification of complement receptor 1 (CR1/CD35) protein clustering in human erythrocytes / J Neuroimmune Pharmacol 7 : 539 ~ 543
Cockburn IA / 2004 / A human complement receptor 1 polymorphism that reduces Plasmodium falciparum rosetting confers protection against severe malaria / Proc Natl Acad Sci U
Cockburn IA / 2006 / Erythrocyte complement receptor 1 (CR1) expression level is not associated with polymorphisms in the promoter or 3’ untranslated regions of the CR1 gen
Fernandez-Arias C / 2013 / Malaria inhibits surface expression of complement receptor 1 in monocytes/macrophages, causing decreased immune complex internalization / J Immuno
Lapin ZJ / 2012 / Near-field quantification of complement receptor 1 (CR1/CD35) protein clustering in human erythrocytes / J Neuroimmune Pharmacol 7 : 539 ~ 543
함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Knowledge, Attitudes and Perceptions Regarding Endemic Vivax Malaria in Inhabitants and Patients in Two Cities of Northern Gyeonggi-do, Korea, 2020
Parasites, Hosts and Diseases
2021 .12
-
Recent Spatial and Temporal Trends of Malaria in Korea
Parasites, Hosts and Diseases
2021 .12
-
Time trend of malaria in relation to climate variability in Papua New Guinea
Environmental Analysis Health and Toxicology
2016 .12
-
Patterns and trends of malaria in 25 risk districts of Nepal from 2001 to 2017
Clinical and Experimental Vaccine Research
2019 .01
-
Imported Malaria over Fifteen Years in an Inner City Teaching Hospital of Washington DC
Parasites, Hosts and Diseases
2016 .06
-
An Evaluation of Active Case Detection in Malaria Control Program in Kiyuni Parish of Kyankwanzi District, Uganda
Parasites, Hosts and Diseases
2018 .12
-
Evaluating the knowledge, attitude, perception, and readiness of caregivers of under 5-year-old children to accept malaria vaccine in Nigeria
Clinical and Experimental Vaccine Research
2024 .04
-
An Epidemiological Analysis of 28 Vivax Malaria Cases in Gimpo-si, Korea, 2020
Parasites, Hosts and Diseases
2021 .10
-
Epidemiological Characteristics of Re-emerging Vivax Malaria in the Republic of Korea (1993-2017)
Parasites, Hosts and Diseases
2018 .12
-
Prevalence of asymptomatic malaria in high- and low-transmission areas of Tanzania: The role of asymptomatic carriers in malaria persistence and the need for targeted surveillance and control efforts
Parasites, Hosts and Diseases
2025 .02
-
Malaria Risk Factors in Kaligesing, Purworejo District, Central Java Province, Indonesia: A Case-control Study
예방의학회지
2018 .01
-
Awareness and Opinions of Inhabitants on Vivax Malaria in Two Endemic Areas, Gyeonggi-do, Korea
Parasites, Hosts and Diseases
2021 .10
-
Spatiotemporal Trends of Malaria in Relation to Economic Development and Cross-Border Movement along the China–Myanmar Border in Yunnan Province
Parasites, Hosts and Diseases
2020 .06
-
Association Study between Norepinephrine Transporter Gene Polymorphism and Schizophrenia in a Korean Population
PSYCHIATRY INVESTIGATION
2015 .01
-
Report of the Korean Association of External Quality Assessment Service on Peripheral Blood Smear Testing for Malaria in 2020
Journal of Laboratory Medicine And Quality Assurance
2021 .12
-
Ethnic Variation and Its Association With Malaria Awareness: A Cross-sectional Study in East Nusa Tenggara Province, Indonesia
예방의학회지
2022 .01
-
Comparative Assessment of Diagnostic Performances of Two Commercial Rapid Diagnostic Test Kits for Detection of Plasmodium spp. in Ugandan Patients with Malaria
Parasites, Hosts and Diseases
2018 .10
-
Blackwater Fever Followed by Severe Falciparum Malaria in a Child
Pediatric Infection and Vaccine
2017 .08
-
Malaria Prevalence in a Low Transmission Area, Jazan District of Southwestern Saudi Arabia
Parasites, Hosts and Diseases
2019 .06
-
Incidental Identification of Plasmodium vivax During Routine Complete Blood Count Analysis Using the UniCel DxH 800
Annals of Laboratory Medicine
2018 .01
이 논문의 저자 정보
최근 본 자료
댓글(0)
0