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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2009.1
- 수록면
- 280 - 283 (4page)
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초록· 키워드
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The prognosis for patients with primary central nervous system (CNS) lymphoma (PCNSL) who relapse after the initial
response is usually poor. A standard treatment for relapsed PCNSL has not yet been identified because of the heterogeneity
of the therapies employed and the lack of large, prospective clinical trials. We describe a 46-year-old relapsed PCNSL
patient who was successfully treated with intraventricular applications of rituximab to minimize neurotoxicity, 2 cycles of
salvage chemotherapy with etoposide, ifosfamide, and cytarabine (VIA) regimen and high-dose chemotherapy with
autologous stem cell rescue. The high-dose chemotherapy consisted of bischloroethylnitrosourea, etoposide, cytarabine, and
melphalan (BEAM) regimen. Partial remission was detected after intraventricular rituximab therapy and the patient has been
in complete remission without evidence of neurotoxicity for 28 months after high-dose chemotherapy with autologous stem
cell rescue. This case indicates a new appropriate treatment guideline in relapsed PCNSL patient after initial intensive
chemo-radiotherapy.
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등록된 정보가 없습니다.
참고문헌 (16)
참고문헌 신청
Akyuz C / 2007 / Successful use of intraventricular and intravenous rituximab therapy for refractory primary CNS lymphoma in a child / Leuk Lymphoma 48 : 1253 ~ 1255
Arellano-Rodrigo E / 2003 / Salvage treatment with etoposide (VP-16), ifosfamide and cytarabine (Ara-C) for patients with recurrent primary central nervous system lymphoma /
Batchelor T / 2006 / Primary CNS lymphoma / J Clin Oncol 24 : 1281 ~ 1288
Ferreri AJ / 2000 / Therapeutic management of primary central nervous system lymphoma: lessons from prospective trials / Ann Oncol 11 : 927 ~ 937
Ferreri AJ / 2002 / multicenter study of treatment of primary CNS lymphoma / Neurology 58 : 1513 ~ 1520
Arellano-Rodrigo E / 2003 / Salvage treatment with etoposide (VP-16), ifosfamide and cytarabine (Ara-C) for patients with recurrent primary central nervous system lymphoma /
Batchelor T / 2006 / Primary CNS lymphoma / J Clin Oncol 24 : 1281 ~ 1288
Ferreri AJ / 2000 / Therapeutic management of primary central nervous system lymphoma: lessons from prospective trials / Ann Oncol 11 : 927 ~ 937
Ferreri AJ / 2002 / multicenter study of treatment of primary CNS lymphoma / Neurology 58 : 1513 ~ 1520
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