지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2012.1
- 수록면
- 181 - 185 (5page)
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초록· 키워드
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Purpose: During stimulated in vitro fertilization (IVF) cycle, up to 30% of the recovered oocytes are immature ones which have poor fertilization capacity; however,the precise influencing factors are largely unknown. Here, we analyzed the association of oocyte immaturity with woman’s age in IVF cycles stimulated by single regimen. Materials and Methods: A total of one-hundred ninety five IVF cycles stimulated by recombinant FSH and GnRH antagonist protocol between 2003 and 2009 were analyzed retrospectively. The mean age of women was 34.2±4.0 (26-45 years). After triggering by exogenous hCG, an ultrasound-guided retrieval of oocytes was performed 35-36 hours later. All clinical data were stratified by woman’s age; group I: ≤30 (n=36), II: 31-35 (n=83), III: 36-40 (n=57), and IV: ≥41 (n=19). Results: The total retrieved oocytes, as well as immature oocytes, were significantly lower in group IV, however, the mean % of immature oocytes was significantly higher in group IV than other age groups. Oocyte immaturity tended to decrease as increasing age in women aged 40 years or less. Conclusion: In stimulated IVF cycle, much higher oocyte immaturity was noted in women aged 41 years or more.
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참고문헌 (19)
참고문헌 신청
Baker VL / 2009 / Clinical efficacy of highly purified urinary FSH versus recombinant FSH in volunteers undergoing controlled ovarian stimulation for in vitro fertilization:
Bosch E / 2008 / Highly purified hMG versus recombinant FSH in ovarian hyperstimulation with GnRH antagonists--a randomized study / Hum Reprod 23 : 2346 ~ 2351
Cha KY / 1998 / Maturation in vitro of immature human oocytes for clinical use / Hum Reprod Update 4 : 103 ~ 120
Chian RC / 2004 / Natural-cycle in vitro fertilization combined with in vitro maturation of immature oocytes is a potential approach in infertility treatment / Fertil Steril
De Vos A / 1999 / In-vitro matured metaphase-I oocytes have a lower fertilization rate but similar embryo quality as mature metaphase-II oocytes after intracytoplasmic sperm
Bosch E / 2008 / Highly purified hMG versus recombinant FSH in ovarian hyperstimulation with GnRH antagonists--a randomized study / Hum Reprod 23 : 2346 ~ 2351
Cha KY / 1998 / Maturation in vitro of immature human oocytes for clinical use / Hum Reprod Update 4 : 103 ~ 120
Chian RC / 2004 / Natural-cycle in vitro fertilization combined with in vitro maturation of immature oocytes is a potential approach in infertility treatment / Fertil Steril
De Vos A / 1999 / In-vitro matured metaphase-I oocytes have a lower fertilization rate but similar embryo quality as mature metaphase-II oocytes after intracytoplasmic sperm
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