지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2014.1
- 수록면
- 904 - 911 (8page)
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Purpose: Coronary flow reserve (CFR) in the non-infarcted myocardium is often impairedfollowing acute myocardial infarction (AMI). However, the clinical significanceof CFR in the non-infarcted myocardium is not fully understood. The objective of the present study was to assess whether a relationship exists between CFR and left ventricular remodeling following AMI. Materials and Methods: We enrolled 18 consecutive patients undergoing coronary intervention. Heart function was analyzed using real-time myocardial contrast echocardiography at one week and six months aftercoronary angioplasty. Ten subjects were enrolled as the control group and were examinedusing the same method at the same time to assess CFR. Cardiac troponin I (cTnI) levels were routinely analyzed to estimate peak concentration. Results: CFR was 1.55±0.11 in the infarcted zone and 2.05±0.31 in the remote zone (p<0.01) at one week following AMI. According to CFR values in the remote zone, all patients were divided into two groups: Group I (CFR <2.05) and Group II (CFR >2.05). The levels of cTnI were higher in Group I compared to Group II on admission (36.40 vs. 21.38, p<0.05). Furthermore, left ventricular end diastolic volume was higher in Group I compared to Group II at six months following coronary angioplasty. Conclusion: Microvasculardysfunction is commonly observed in the remote myocardium. The CFR value accurately predicts adverse ventricular remodeling following AMI.
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참고문헌 (19)
참고문헌 신청
박성미 / 2010 / Predicting Myocardial Functional Recovery After Acute Myocardial Infarction: Relationship Between Myocardial Strain and Coronary Flow Reserve / Korean Circulation Journal 40(12):639~644
Anantharam B / 2011 / Coronary flow reserve assessed by myocardial contrast echocardiography predicts mortality in patients with heart failure / Eur J Echocardiogr 12 : 69 ~
Armstrong WF / 2005 / Stress echocardiography: current methodology and clinical applications / J Am Coll Cardiol 45 : 1739 ~ 1747
Bodi V / 2007 / Abnormal myocardial perfusion after infarction in patients with persistent TIMI grade-3 flow. Only an acute phenomenon? / Rev Esp Cardiol 60 : 486 ~ 492
Bolognese L / 2004 / Impact of microvascular dysfunction on left ventricular remodeling and long-term clinical outcome after primary coronary angioplasty for acute myocardia
Anantharam B / 2011 / Coronary flow reserve assessed by myocardial contrast echocardiography predicts mortality in patients with heart failure / Eur J Echocardiogr 12 : 69 ~
Armstrong WF / 2005 / Stress echocardiography: current methodology and clinical applications / J Am Coll Cardiol 45 : 1739 ~ 1747
Bodi V / 2007 / Abnormal myocardial perfusion after infarction in patients with persistent TIMI grade-3 flow. Only an acute phenomenon? / Rev Esp Cardiol 60 : 486 ~ 492
Bolognese L / 2004 / Impact of microvascular dysfunction on left ventricular remodeling and long-term clinical outcome after primary coronary angioplasty for acute myocardia
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