지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2012.1
- 수록면
- 543 - 549 (7page)
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초록· 키워드
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Purpose: The aim of this study was to evaluate the recent changes in the clinicopathologic features of prostate cancer in Korea and to compare these features with those of Western populations. Materials and Methods: We retrospectively reviewed the data of 1582 men undergoing radical prostatectomy for clinically localized prostate cancer between 1995 and 2007 at 10 institutions in Korea for comparison with Western studies. The patients were divided into two groups in order to evaluate the recent clinicopathological changes in prostate cancer: Group 1 had surgery between 1995 and 2003 (n=280) and Group 2 had surgery between 2004 and 2007 (n=1302). The mean follow-up period was 24 months. Results: Group 1 had a higher prostate-specific antigen level than Group 2 (10.0 ng/mL vs. 7.5 ng/mL, respectively;p<0.001) and a lower proportion of biopsy Gleason scores ≤6 (35.0% vs. 48.1%, respectively; p<0.001). The proportion of patients with clinical T1 stage was higher in Group 2 than in Group 1. Group 1 had a lower proportion of organ-confined disease (59.6% vs. 68.6%; p<0.001) and a lower proportion of Gleason scores ≤6 (21.3% vs. 33.0%; p<0.001), compared to Group 2. However, the relatively higher proportion of pathologic Gleason scores ≤6 in Group 2 was still lower than those of Western men, even though the proportion of organ-confined disease reached to that of Western series. Conclusion: Korean men with prostate cancer currently present better clinicopathologic parameters. However, in comparison, Korean men still show relatively worse pathologic Gleason scores than Western men.
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참고문헌 (26)
참고문헌 신청
Schroeck FR / 2009 / Do nomograms predict aggressive recurrence after radical prostatectomy more accurately than biochemical recurrence alone? / BJU Int 103:603~608
Capitanio U / 2009 / The probability of Gleason score upgrading between biopsy and radical prostatectomy can be accurately predicted / Int J Urol 16:526~529
/ / Korea Statistical Information Service
/ / http://www.ncc.re.kr
Cohen JH / 2006 / Racial differences in clinical progression among Medicare recipients after treatment for localized prostate cancer (United States) / Cancer Causes Control
Capitanio U / 2009 / The probability of Gleason score upgrading between biopsy and radical prostatectomy can be accurately predicted / Int J Urol 16:526~529
/ / Korea Statistical Information Service
/ / http://www.ncc.re.kr
Cohen JH / 2006 / Racial differences in clinical progression among Medicare recipients after treatment for localized prostate cancer (United States) / Cancer Causes Control
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