지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2014.1
- 수록면
- 34 - 40 (7page)
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초록· 키워드
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Objectives: The objective of the present study was to investigate the lipid and the antioxidant regulatory potential of a multigrain diet in laboratory animals with reference to lipid profiles, tissue lipid peroxidation and antioxidant status.
Methods: Two types of diets, with or without addition of cholesterol, were used in the study – a commercial diet and a formulated multigrain diet (with Sorghum vulgare, Avena sativa, Pennisetum typhoideum, Oryza sativa, Eleusine coracana and Zea mays grains). After a 10-week period of feeding the diets to albino rats the plasma, liver and fecal lipid profiles and the hepatic and renal antioxidant status of the animals that were fed the commercial and the formulated diets (with and without cholesterol addition) were assessed.
Results: The commercial diet supplemented with cholesterol elevated the levels of plasma total lipids, total cholesterol, triglycerides, low-density lipoprotein cholesterol (LDL-C), and very low-density lipoprotein cholesterol (VLDL-C), as well as the atherogenic index (AI). The high-density lipoprotein cholesterol (HDL-C) content and the antioxidant profiles (total ascorbic acid, superoxide dismutase, catalase, glutathione peroxidase reduced glutathione) declined along with increases in lipid peroxidation. The formulated diet (with and without addition of cholesterol) was found to be more efficient than the commercial diet in controlling plasma, hepatic and fecal lipid profiles, as well as hepatic and renal lipid peroxidation and antioxidant status, than of the hypercholesteremic animals.
Conclusion: The multigrain diet used in the present study is effective in countering the hyperlipidemia and oxidative stress caused by high cholesterol intake.
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참고문헌 (39)
참고문헌 신청
Malencic D. / 2007 / Phenolic content and antioxidant properties of soybean(Glycine max(L.)Merr. )seeds / Molecules 12(3):576~581
Yun S. / 2009 / Total phenolics, flavonoids, antioxidant capacity in rice grain and their relations to grain color, size and weight / J Cereal Sci 49(1):106~111
Awika JM. / 2004 / Sorghum phytochemicals and their potential impact on human health / Phytochemistry 65(9):1199~1221
Lim TK. / 2013 / Edible Medicinal and Non-Medicinal Plants: Volume 5 / Springer :416~447
Palanisamy BD / 2011 / Health benefits of finger millet (Eleusine coracana L.) polyphenols and dietary fiber: a review / J Food Sci Technol
Yun S. / 2009 / Total phenolics, flavonoids, antioxidant capacity in rice grain and their relations to grain color, size and weight / J Cereal Sci 49(1):106~111
Awika JM. / 2004 / Sorghum phytochemicals and their potential impact on human health / Phytochemistry 65(9):1199~1221
Lim TK. / 2013 / Edible Medicinal and Non-Medicinal Plants: Volume 5 / Springer :416~447
Palanisamy BD / 2011 / Health benefits of finger millet (Eleusine coracana L.) polyphenols and dietary fiber: a review / J Food Sci Technol
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