지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2013.1
- 수록면
- 1 - 6 (6page)
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Various biomaterials are used in dental surgeries, including oral maxillofacial, periodontal, and implant surgeries. There is currently much research on synthetic bone grafts. Since synthetic bone lacks an osteo-induction effect despite having osteo-conduction, efforts have been made to increase the rate and quantity of bone formation as well as accelerate the rate of regeneration of damaged tissues by using a mixture of synthetic bone and materials having bone-inducing effects, such as growth factors and bone-formation proteins. The representative material among these is platelet-rich fibrin, which contains osteo-inducing growth factors from autogenous blood. Ten males in their 20s who do not smoke and are healthy without any systemic diseases were selected for the extraction of 20 mL of blood. After centrifuging blood, platelet-rich fibrin was obtained. Exudates were extracted by putting the blood in a bowl for 10 minutes. After preserving the extracted exudates at -70oC, enzyme-linked immunosorbent assay analysis was performed for quantitative evaluation of three growth factors, platelet-derived growth factor BB, insulin-like growth factor-1, and vascular endothelial growth factor. In this study, basic evidence about the clinical use of platelet-rich fibrin in various dental surgeries was obtained, and the role of platelet-rich fibrin was also elucidated by examining the roles of the three growth factors.
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참고문헌 (24)
참고문헌 신청
Aghaloo TL / 2002 / Investigation of platelet-rich plasma in rabbit cranial defects: A pilot study / J Oral Maxillofac Surg 60 : 1176 ~ 1181
Anitua E / 1999 / Plasma rich in growth factors: preliminary results of use in the preparation of future sites for implants / Int J Oral Maxillofac Implants 14 : 529 ~ 535
Bauer EA / 1985 / Stimu-lation of in vitro human skin collagenase expression by platelet-derived growth factor / Proc Natl Acad Sci U S A 82 : 4132 ~ 4136
Canalis E / 1989 / Insulin-like growth factor I mediates selective anabolic effects of parathyroid hormone in bone cultures / J Clin Invest 83 : 60 ~ 65
Choukroun J / 2006 / Platelet-rich fibrin (PRF): a second-generation platelet concentrate. Part IV: clinical e°ects on tissue healing / Oral Surg Oral Med Oral Pathol Oral
Anitua E / 1999 / Plasma rich in growth factors: preliminary results of use in the preparation of future sites for implants / Int J Oral Maxillofac Implants 14 : 529 ~ 535
Bauer EA / 1985 / Stimu-lation of in vitro human skin collagenase expression by platelet-derived growth factor / Proc Natl Acad Sci U S A 82 : 4132 ~ 4136
Canalis E / 1989 / Insulin-like growth factor I mediates selective anabolic effects of parathyroid hormone in bone cultures / J Clin Invest 83 : 60 ~ 65
Choukroun J / 2006 / Platelet-rich fibrin (PRF): a second-generation platelet concentrate. Part IV: clinical e°ects on tissue healing / Oral Surg Oral Med Oral Pathol Oral
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