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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2015.1
- 수록면
- 127 - 134 (8page)
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초록· 키워드
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ABSTRACT Purpose: The purpose of this study was to investigate cell attachment characteristics of nanotubes on the surface of Ti-6Al-4V dental implant alloy.
Materials and Methods: TiO2 nanotubes were formed on the Ti-6Al-4V alloys by anodic oxidation. The electrolyte solution was prepared by adding H3PO4 solution to 0.8 wt% NaF solution and then stirred with a magnetic stirrer. With a platinum electrode and a saturated calomel electrode, electrochemical experiments were performed using a conventional three-electrode configuration. Anodic oxidation was carried out using a scanning potentiostat, and all experiments were proceeded as planed at room temperature. Crystallization treatment of nanotube surface went off at 450oC for 3 hours. MC3T3-E1 cell culture was performed with MC3T3-E1 mouse osteoblast for 2 days.
Results: Microstructure of the alloys and nanotube surface were observed by optical microscope, field emission scanning electron microscope, and crystallization of nanotube was identified by X-ray diffractometer.
Conclusion: The formation of the nanotube structure on the Ti-6Al-4V alloy significantly increased the surface area, which could be useful for the adsorption and adhesion enhancements of cells and could be applied for drug delivery system.
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참고문헌 (23)
참고문헌 신청
Agrawal CM / 1998 / Reconstructing the human body using biomaterials / JOM 50 : 31 ~ 35
Ahmed T / 1995 / A new modulus, biocompatible titanium alloy. Titanium / Titanium 95 Sci Tech 2 : 1760 ~ 1767
Branemark PI / 1983 / Osseointegration and its experimental background / J Prosthet Dent 50 : 399 ~ 410
Donachie M / 1998 / Biomedical alloys / Adv Mater Process 154 : 63 ~ 65
Farrar G / 1990 / Defective gallium-transferrin binding in Alzheimer disease and Down syndrome: possible mechanism for accumulation of aluminium in brain / Lancet 335 : 747 ~
Ahmed T / 1995 / A new modulus, biocompatible titanium alloy. Titanium / Titanium 95 Sci Tech 2 : 1760 ~ 1767
Branemark PI / 1983 / Osseointegration and its experimental background / J Prosthet Dent 50 : 399 ~ 410
Donachie M / 1998 / Biomedical alloys / Adv Mater Process 154 : 63 ~ 65
Farrar G / 1990 / Defective gallium-transferrin binding in Alzheimer disease and Down syndrome: possible mechanism for accumulation of aluminium in brain / Lancet 335 : 747 ~
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