지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2011.1
- 수록면
- 37 - 45 (9page)
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Objectives: Obesity and osteoporosis have been increasing for decades but their relationship to bone mineral density (BMD) and fat mass has not been defined. The aim of this study was to investigate how changes in body composition affect BMD after a weight reduction.
Materials and Methods: We reviewed 48 middle-aged obese women who had participated in our diet program and succeeded in reducing their weight. Body composition was measured by the dual-energy X-ray absorptiometry method, and metabolic syndrome was defined as described in the ATP-III guidelines. All differences between baseline and 12 weeks later were expressed as [{12th week data–baseline data}/baseline data×100].
Results: The mean age of the participants was 38.29±10.89 years, and the mean follow-up time was 85 days. The mean body mass index was 31.50±5.19 kg/m^2. Basal BMD decreased with age and increased with weight and appendicular lean mass. In a regression analysis, appendicular lean mass was positively correlated with leg BMD (R^62=0.235, B=0.015, P<0.001) and age (B=-0.002, P=0.046), and appendicular lean mass (B=0.019, P=0.049) was the main determinant of total BMD (R^2=0.272). After weight reduction, the total body BMD change ratio (R^2=0.281) was negatively related to the change of fat mass, trunk fat mass (B=-0.042, P=0.087) and waist circumference (B=-0.108, P=0.014)Conclusions: Our findings suggest that BMD is determined by muscle mass, and that changes in central obesity may also affect BMD.
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참고문헌 (23)
참고문헌 신청
Beck TJ / 2001 / Structural adaptation to changing skeletal load in the progression toward hip fragility: the study of osteoporotic fractures / J Bone Miner Res 16 (6) : 1108
Bjorntorp P / 1991 / Metabolic implications of body fat distribution / Diabetes Care 14 (12) : 1132 ~ 1143
Burr DB / 1997 / Muscle strength, bone mass, and agerelated bone loss / J Bone Miner Res 12 (10) : 1547 ~ 1551
Compston JE / 1992 / Effect of diet-induced weight loss on total body bone mass / Clin Sci (Lond) 82 (4) : 429 ~ 432
Crespo NC / 2011 / Anthropometric and Lifestyle Associations of Bone Mass in Healthy Pre-Menopausal Mexican and Asian American Women / J Immigr Minor Health 13 (1) : 74 ~ 80
Bjorntorp P / 1991 / Metabolic implications of body fat distribution / Diabetes Care 14 (12) : 1132 ~ 1143
Burr DB / 1997 / Muscle strength, bone mass, and agerelated bone loss / J Bone Miner Res 12 (10) : 1547 ~ 1551
Compston JE / 1992 / Effect of diet-induced weight loss on total body bone mass / Clin Sci (Lond) 82 (4) : 429 ~ 432
Crespo NC / 2011 / Anthropometric and Lifestyle Associations of Bone Mass in Healthy Pre-Menopausal Mexican and Asian American Women / J Immigr Minor Health 13 (1) : 74 ~ 80
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