지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2015.1
- 수록면
- 81 - 87 (7page)
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Introduction: Osteoporotic vertebral fractures, which account for the largest part of the disease has become important and common diseases. We studied persistence for osteoporosis medication and its related factor in patients with osteoporotic compression vertebral fracture.
Methods: A total of 458 patients that visited our outpatient clinic with osteoporotic vertebral fractures and were prescribed with osteoporosis medication at the Seoul Spine Center from January 2010 to February 2014 and were analyzed retrospectively. The male to female ratio was 403: 55 and the mean age was 75 years. Survival analysis was used with the Kaplan-Meier method. Related factor analysis was performed with the log rank test and Cox regression test.
Results: The survival rate at 6 months was 52%, 12 months was 40%, 24 months was 28%, and at 3 years it was 25%. There was no difference between the persistent rate according to age. Women demonstrated higher persistent rate than men in significantly. It showed a significant difference between some of the groups in accordance with the dose rate and duration of the drug dose interval. Especially, medication change group had significant higher persistence rate than not changing group.
Conclusions: Persistence rate of osteoporosis drugs, decreased rapidly with the passage of time. The patients with changing medication during follow-up had significantly higher persistence ratio than those without it. The persistence rate of osteoporosis medication could be increased through actively solving the problems of the patients, which are associated with taking medication.
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참고문헌 (20)
참고문헌 신청
Andrade SE / 2006 / Methods for evaluation of medication adherence an persistence using automated databases / Pharmacoepidemiology and Drug Safety 15 : 565 ~ 574
Arden N / 2006 / Persistence with teriparatide in patients with osteoporosis: the UK experience / Osteoporosis International 17 : 1626 ~ 1629
Barbosa CD / 2012 / A literature review to explore the link between treatment satisfaction and adherence, compliance, and persistence / Patient Prefer Adherence 6 : 39 ~ 48
Carr AJ / 2006 / Factors associated with adherence and persistence to bisphosphonate therapy in osteoporosis: a cross-sectional survey / Osteoporosis International 17 : 1638
Choi YJ / 2012 / The prevalence of osteoporosis in Korean adults aged 50 years or older and the higher diagnosis rates in women who were beneficiaries of a national screening
Arden N / 2006 / Persistence with teriparatide in patients with osteoporosis: the UK experience / Osteoporosis International 17 : 1626 ~ 1629
Barbosa CD / 2012 / A literature review to explore the link between treatment satisfaction and adherence, compliance, and persistence / Patient Prefer Adherence 6 : 39 ~ 48
Carr AJ / 2006 / Factors associated with adherence and persistence to bisphosphonate therapy in osteoporosis: a cross-sectional survey / Osteoporosis International 17 : 1638
Choi YJ / 2012 / The prevalence of osteoporosis in Korean adults aged 50 years or older and the higher diagnosis rates in women who were beneficiaries of a national screening
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