지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2011.1
- 수록면
- 409 - 411 (3page)
이용수
초록· 키워드
오류제보하기
In Korea, pulmonary surfactant (PS) replacement therapy in respiratory distress syndrome (RDS) was started in 1991 since when Surfacten^® was imported from Japan. At the present time, Surfacten^®, Newfactan^®, Curosurf^®, and Infasurf^® are available in Korea. The governmental health insurance covers the expense for multiple dose treatment since 2002 and the early prophylactic treatment (BW: <1,250 g or GP: <30 wks) since 2011. We undertook a multi-institutional collective study to evaluate the outcomes of PS over past 20 years in Korea (Period-I; 1990/91, P-II; 1996, P-III; 2002, and P-IV; 2007, P-V; 2010). There were 60 RDS neonates with PS treatment in P-I (16 hospitals), 1,179 in P-II (64), 1,595 in P-III (62), 1,921 in P-IV (57), and 3,160 in P-V (72). Decreased mortality rate, defined as the percentage of neonates who died within 28 days of birth, was seen between periods, P-V vs P-I, II, III,and IV (mortality rate: 10.1% vs. 40.0%, 30.0%, 18.7%, and 14.3%). We conclude that PS therapy contributed to improve remarkable outcome in RDS neonates over the last 20 years in Korea. However, more efforts should be made to optimize PS therapy for better outcome. Multiple PS doses for relapse and poor response, early prophylactic use, and better supportive care for pre-term infants are mandatory.
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참고문헌 (11)
참고문헌 신청
/ / Intercontinental Medical Statistics Korea
Bae CW / 1993 / Surfactant replacement therapy in neonates with respiratory distress syndrome: a collective evaluation of trials from 16 hospitals / J Korean Pediatr Soc 36 :
Bae CW / 1997 / Surfactant replacement therapy in RDS: a collaborative study of multi-center trials in Korea / J Korean Soc Neonatol 1 : 124 ~ 135
Fujiwara T / 1980 / Artificial surfactant therapy in hyaline-membrane disease / Lancet 1 : 55 ~ 59
Halliday HL / 2008 / Surfactants: past, present and future / J Perinatol 28 (Suppl 1) : S47 ~ S56
Bae CW / 1993 / Surfactant replacement therapy in neonates with respiratory distress syndrome: a collective evaluation of trials from 16 hospitals / J Korean Pediatr Soc 36 :
Bae CW / 1997 / Surfactant replacement therapy in RDS: a collaborative study of multi-center trials in Korea / J Korean Soc Neonatol 1 : 124 ~ 135
Fujiwara T / 1980 / Artificial surfactant therapy in hyaline-membrane disease / Lancet 1 : 55 ~ 59
Halliday HL / 2008 / Surfactants: past, present and future / J Perinatol 28 (Suppl 1) : S47 ~ S56
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