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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2017.1
- 수록면
- 28 - 34 (7page)
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Purpose: The aim of this study was to determine the prevalence and disease-specific antimicrobial susceptibility of Escherichia coli in urinary tract infections (UTIs).Materials and Methods: A total of 862 patients older than 18 years of age, who were diagnosed with UTI between January 2013 and December 2015, were included. The results of urine culture, prevalence of extended-spectrum beta lactamase (ESBL)-producing E. coli, and antimicrobial susceptibility by disease were also examined. Results: A total of 862 uropathogens were isolated. Among then, E. coli accounted for 756 (87.7%) isolates. The susceptibility rates of E. coli to the following antimicrobial agents were as follows: ampicillin 29.4%, cefazolin 70.5%, ceftazidime 75.1%, cefotaxime 75.0%, cefepime 76.2%, cefoxitin 88.8%, amoxicillin-clavulanic acid 63.6%, trimethoprim-sulfamethoxazole 60.6%, gentamicin 71.4%, ciprofloxacin 73.0%, piperacillin/tazobactam 93.9%, amikacin 99.2%, imipenem 99.1%, and ertapenem 99.3%. The frequency of ESBL-producing E. coli strains was 24.6%. The antimicrobial susceptibility of UTI varied by each disease, but without statistical significance.Conclusions: It is necessary to regularly examine the disease-specific resistance rates to determine the appropriate empiric antibiotic treatment, and the national antibiotic usage policies must be reorganized according to the data obtained from these studies.
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참고문헌 (18)
참고문헌 신청
De Backer D / 2008 / Evolution of bacterial susceptibility pattern of Escherichia coli in uncomplicated urinary tract infections in a country with high antibiotic consumption
Dielubanza EJ / 2011 / Urinary tract infections in women / Med Clin North Am 95 : 27 ~ 41
Flores-Mireles AL / 2015 / Urinary tract infections: epidemiology, mechanisms of infection and treatment options / Nat Rev Microbiol 13 : 269 ~ 284
Goettsch W / 2000 / Increasing resistance to fluoroquinolones in escherichia coli from urinary tract infections in the Netherlands / J Antimicrob Chemother 46 : 223 ~ 228
Gupta K / 2011 / International clinical practice guidelines for the treatment of acute uncomplicated cystitis and pyelonephritis in women:A 2010 update by the Infectious Dis
Dielubanza EJ / 2011 / Urinary tract infections in women / Med Clin North Am 95 : 27 ~ 41
Flores-Mireles AL / 2015 / Urinary tract infections: epidemiology, mechanisms of infection and treatment options / Nat Rev Microbiol 13 : 269 ~ 284
Goettsch W / 2000 / Increasing resistance to fluoroquinolones in escherichia coli from urinary tract infections in the Netherlands / J Antimicrob Chemother 46 : 223 ~ 228
Gupta K / 2011 / International clinical practice guidelines for the treatment of acute uncomplicated cystitis and pyelonephritis in women:A 2010 update by the Infectious Dis
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