유두 갑상선암에서 종양 크기에 따른 림프절 전이 양상

유영범; 김건; 강현종; 박경식; 백남선

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자료유형: 학술저널

저자정보: 유영범 김건 강현종 박경식 백남선

저널정보: 대한갑상선-내분비외과학회 The Journal of Endocrine Surgery The Journal of Endocrine Surgery 제10권 제4호

발행연도: 2010.1

수록면: 256 - 260 (5page)

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연구주제

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연구방법

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Purpose: Prognosis of papillary thyroid carcinoma (PTC) is very favorable, but PTC frequently invade adjacent soft tissue and metastases to cervical lymph node. We evaluated the pattern of cervical neck lymph node metastasis in PTC according to tumor size. Methods: From August 2005 to January 2009, 353 patients were underwent surgery for PTC. Among these patients, total thyroidectomy with cervical neck lymph node dissection were done in 266 patients. We subdivided patients into four groups according to size and compared the clinicopathologic characters between groups. And we confirmed the factors affecting central neck node metastasis. Results: The mean age of patients of diagnosis was 49.1 years and female to male ratio was 5.8：1. Cervical lymph node metastasis were in 47.0% of the total cases. Cervical lymph node metastases and invasion to adjacent structure increased with tumor size. But, there were no significant differences in tumor size, invasion to adjacent structure, multifocality or bilaterality according to cervical lymph node metastasis. Early diagnostic age and sexuality were significantly related to cervical lymph node metastasis of PTC. Conclusion: PTC showed the aggressiveness with increasing tumor size. Tumor size was not related to cervical lymph node metastasis. These findings suggest that tumor size can help treat PTC, can`t be used by prediction factor of cervical lymph node metastasis. (Korean J Endocrine Surg 2010;10:256-260)

#유두 갑상선암 #경부 림프절 전이 #종양 크기 #Papillary thyroid carcinoma #Cervical lymph node metastasis #Tumor size

참고문헌 (23)

참고문헌 신청

Bramley MD / 1996 / Papillary microcarcinoma of thyroid gland / Br J Surg 83

Byar DP / 1979 / A prognostic index for thyroid carcinoma. A study of the E.O.R.T.C. Thyroid Cancer Cooperative Group / Eur J Cancer 15 : 1033 ~ 1041

Cady B / 1988 / An expanded view of risk-group definition in differentiated thyroid carcinoma / Surgery 104 : 947 ~ 953

Cooper DS / 2006 / Management guidelines for patients with thyroid nodules and differentiated thyroid cancer / Thyroid 　 16 : 109 ~ 142

Davies L / 2006 / Increasing incidence of thyroid cancer in the United states, 1973-2002 / JAMA 295 : 2164 ~ 2167

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