지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록· 키워드
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Background: The relative importance of body composition, lifestyle factors, bone turn-over and hormonal factors in determining bone mineral density (BMD) is unknown. Westudied younger postmenopausal women to determine whether modifiable or non-modifiable risk factors for osteoporosis have stronger associations with BMD.
Methods: In multivariable linear regression models, we tested associations betweennon-bone body composition measures, self-reported measures of physical activity anddietary intake, urinary N-telopeptide (NTx), sex hormone concentrations, and BMD in109 postmenopausal women aged 50 to 64 years, adjusting for current hormone thera-py use and clinical risk factors for low BMD. Lean mass, fat mass and areal BMD (aBMD)at the lumbar spine, femoral neck, total hip and distal radius were measured using dualenergy X-ray absorptiometry.
Results: Higher body weight and self-reported nonwhite race were independently asso-ciated with higher aBMD at the lumbar spine, femoral neck, total hip and distal radius.
Lean and fat mass were not independently associated with aBMD. Older age and higherurinary NTx were independently associated with lower aBMD at the distal radius but notat weight-bearing sites. Sensitivity analyses demonstrated lack of an independent asso-ciation between total daily protein or calorie intake and BMD.
Conclusions: BMD, weight and race were the most important determinants of aBMD atall sites. Older age and higher bone turnover were independently associated with loweraBMD at the distal radius. In a limited analysis, self-reported physical activity, dietaryprotein and calorie intake were not associated with aBMD after adjustment for the othervariables.
목차
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참고문헌 (36)
참고문헌 신청
Robbins J. / 2006 / Body mass index is not a good predictor of bone density: results from WHI, CHS, and EPIDOS / J Clin Densitom. 9:329~334
김상준 / 2012 / Relationship between Weight, Body Mass Index and Bone Mineral Density of Lumbar Spine in Women / 대한골대사학회지 19(2):95~102
Méndez JP. / 2013 / Bone mineral density in postmenopausal Mexican-Mestizo women with normal body mass index, overweight, or obesity / Menopause. 20:568~572
Gnudi S. / 2007 / Relationship between body composition and bone mineral density in women with and without osteoporosis: relative contribution of lean and fat mass / J Bone Miner Metab. 25:326~332
Liu S. / 2011 / Relationship between body composition and age, menopause and its effects on bone mineral density at segmental regions in Central Southern Chinese postmenopausal elderly women with and without osteoporosis / Arch Gerontol Geriatr. 53:e192~197
김상준 / 2012 / Relationship between Weight, Body Mass Index and Bone Mineral Density of Lumbar Spine in Women / 대한골대사학회지 19(2):95~102
Méndez JP. / 2013 / Bone mineral density in postmenopausal Mexican-Mestizo women with normal body mass index, overweight, or obesity / Menopause. 20:568~572
Gnudi S. / 2007 / Relationship between body composition and bone mineral density in women with and without osteoporosis: relative contribution of lean and fat mass / J Bone Miner Metab. 25:326~332
Liu S. / 2011 / Relationship between body composition and age, menopause and its effects on bone mineral density at segmental regions in Central Southern Chinese postmenopausal elderly women with and without osteoporosis / Arch Gerontol Geriatr. 53:e192~197
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