지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록· 키워드
오류제보하기
Background: Osteoporosis is a progressive bone disease that is characterized by a decrease in bone mass density and destruction of microstructure, which can lead to an increased risk of fracture. Although many studies have been published about the relationship between end-stage renal disease and osteoporosis, research on the relationship between proteinuria and the prevalence of osteoporosis is still lacking. Methods: We assessed 91 postmenopausal women with type 2 diabetes who visited our hospital from January 2009 to January 2012. Results: Among 91 patients, the prevalence of osteoporosis and osteopenia was 35.2% (32 cases) and 32.9% (30 cases) according to bone mineral density. The patients with microalbuminuria and macroalbuminuria (urine albuminto- creatinine ratio [UACR] ≥ 30) had a significantly higher incidence of osteoporosis compared to subjects with normoalbuminuria (P<0.05). Conclusions: This study indicates that UACR may be a useful biomarker for increased risk of osteoporosis in postmenopausal women with type 2 diabetes who have been linked to higher UACR levels.
목차
등록된 정보가 없습니다.
참고문헌 (40)
참고문헌 신청
Kanis JA / 1994 / Assessment of fracture risk and its application to screening for postmenopausal osteoporosis: synopsis of a WHO report. WHO Study Group / Osteoporos Int 4:368~381
Genant HK / 1993 / Vertebral fracture assessment using a semiquantitative technique / J Bone Miner Res 8:1137~1148
Weitzmann MN / 2006 / Estrogen deficiency and bone loss : an inflammatory tale / J Clin Invest 116:1186~1194
Leidig-Bruckner G / 2001 / Diabetes mellitus a risk for osteoporosis? / Exp Clin Endocrinol Diabetes 109(Suppl 2):S493~S514
Räkel A / 2008 / Osteoporosis among patients with type 1 and type 2 diabetes / Diabetes Metab 34:193~205
Genant HK / 1993 / Vertebral fracture assessment using a semiquantitative technique / J Bone Miner Res 8:1137~1148
Weitzmann MN / 2006 / Estrogen deficiency and bone loss : an inflammatory tale / J Clin Invest 116:1186~1194
Leidig-Bruckner G / 2001 / Diabetes mellitus a risk for osteoporosis? / Exp Clin Endocrinol Diabetes 109(Suppl 2):S493~S514
Räkel A / 2008 / Osteoporosis among patients with type 1 and type 2 diabetes / Diabetes Metab 34:193~205
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