지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2013.1
- 수록면
- 64 - 68 (5page)
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초록· 키워드
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Background and Objectives: Cardiovascular symptoms are integral and often the most predominant clinical presentation in patients with thyrotoxicosis. In patients with known or suspected coronary artery disease, myocardial ischemia and angina-like chest pain may be presented due to increase in cardiac output and cardiac contractility as a result of thyrotoxicosis. In addition, coronary spasm may result in angina-like chest pain in thyrotoxicosis patients without any fixed coronary artery stenosis. However, there are few reports about clinical characteristics of thyrotoxicosis associated with coronary artery spasm. Materials and Methods: Coronary angiography, thyroid function test, and follow-up clinical data of patients were analyzed retrospectively. Results: Twelve patients with coronary artery spasm were included over 4.5 years (male：female, 5：7). The mean age of patients was 53.3 years (range, 27 to 68), and female patients were younger than male patients (mean, 56.2 vs. 51.2 years). Only 4 patients (33%) presented typical thyrotoxic symptoms. The causes of thyrotoxicosis were Grave’s disease (75%) and painless thyroiditis (25%). On coronary angiography, severe coronary spasm was observed by provocation in 6 patients, and total occlusion of right coronary artery and left circumflex artery with chest pain developed in 2 of 6 patients. After antithyroid treatment, all patients became free of chest pain. Conclusion: Severe coronary artery spasm can be associated with thyrotoxicosis. Thyroid function test might be a differential diagnostic test in patients with coronary artery spasm. It should be considered that thyrotoxicosis can be presented by coronary artery spasm without typical symptom of thyrotoxicosis.
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참고문헌 (14)
참고문헌 신청
Al Jaber J / 2010 / Thyrotoxicosis and coronary artery spasm: case report and review of the literature / Angiology 61 (8) : 807 ~ 812
Bertrand ME / 1982 / Frequency of provoked coronary arterial spasm in 1089 consecutive patients undergoing coronary arteriography / Circulation 65 (7) : 1299 ~ 1306
Choi YH / 2005 / Severe coronary artery spasm can be associated with hyperthyroidism / Coron Artery Dis 16 (3) : 135 ~ 139
Chudleigh RA / 2007 / Graves' thyrotoxicosis and coronary artery spasm / Postgrad Med J 83 (985) : e5 ~
Ihm SH / 2001 / Morphologic differences of vessel wall at sites of focal and diffuse coronary vasospasm by intravascular ultrasound (IVUS) / Korean Circ J 31 (8) : 749 ~ 756
Bertrand ME / 1982 / Frequency of provoked coronary arterial spasm in 1089 consecutive patients undergoing coronary arteriography / Circulation 65 (7) : 1299 ~ 1306
Choi YH / 2005 / Severe coronary artery spasm can be associated with hyperthyroidism / Coron Artery Dis 16 (3) : 135 ~ 139
Chudleigh RA / 2007 / Graves' thyrotoxicosis and coronary artery spasm / Postgrad Med J 83 (985) : e5 ~
Ihm SH / 2001 / Morphologic differences of vessel wall at sites of focal and diffuse coronary vasospasm by intravascular ultrasound (IVUS) / Korean Circ J 31 (8) : 749 ~ 756
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