메뉴 건너뛰기
.. 내서재 .. 알림
소속 기관/학교 인증
인증하면 논문, 학술자료 등을  무료로 열람할 수 있어요.
한국대학교, 누리자동차, 시립도서관 등 나의 기관을 확인해보세요
(국내 대학 90% 이상 구독 중)
로그인 회원가입 고객센터 ENG
주제분류

추천
검색

논문 기본 정보

자료유형
학술저널
저자정보
저널정보
한국피부과학연구원 아시안뷰티화장품학술지 아시안뷰티화장품학술지 제13권 제4호
발행연도
2015.1
수록면
461 - 468 (8page)

이용수

표지
📌
연구주제
📖
연구배경
🔬
연구방법
🏆
연구결과
AI에게 요청하기
추천
검색

초록· 키워드

오류제보하기
Cornus officianalis has been used in oriental medicine and has been reported to have many functions such as reduction of melanin production, anti-cancer, antibacterial function, and etc.. In this study, we investigated the reduction of pro-inflammatory factor as a functional ingredient for cosmetic products from the 80% ethanol extract of Cornus officianalis fruit (CEE). We performed MTT assay for cell viability. Major inflammatory factors was measured by nitric oxide (NO) inhibition assay, immunoassay, and reverse transcription factor (RT-PCR). The cytotoxicity of CEE did not appear in the range of 125 μg/mL, 250 μg/mL, 500 μg/mL on RAW 264.7 cells. Inflammatory response on RAW 264.7 cells were induced by lipopolysaccharide (LPS), followed by CEE treatment at indicated concentrations (0 μg/mL, 125 μg/mL, 250 μg/mL, and 500 μg/mL). The CEE showed inhibitory effect on production of NO by 5.9%, 21.3%, and 34% at 125 μg/mL, 250 μg/mL, and 500 μg/mL concentrations. In addition, production of prostaglandin E2 (PGE2) was decreased by approximately 3%, 15%, and 39%, upon the CEE treatment at concentrations of 125 μg/mL, 250 μg/mL, and 500 μg/mL respectively. The production of interleukin (IL)-1β, IL-6, and tumor necrosis factor (TNF)-α were decreased by approximately 57%, 52% and 34%, respectively upon CEE treatment at 500 μg/mL. Also, CEE showed inhibitory effects on the expression of IL-1β, IL-6, and TNF-α genes on LPS-induced RAW 264.7 cells. From the results above, we conclude that CEE indicated significant anti-inflammatory effects. And these results will be a basis for the development of cosmetology in skin care and improvement of skin problem.

목차

등록된 정보가 없습니다.

참고문헌 (31)

참고문헌 신청

함께 읽어보면 좋을 논문

논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!

이 논문의 저자 정보

최근 본 자료

전체보기

댓글(0)

0