지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2013.1
- 수록면
- 877 - 882 (6page)
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초록· 키워드
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In order to study about human skin anti-wrinkle effect of red ginseng, red ginseng extracts and the fractions were tested to inhibition effect against MMP-2, -9, and -1 expression in human fibroblast cells by gelatin zymography and RT-PCR methods. The red ginseng samples are red ginseng extract extracted with hot water,crude saponin as butanol soluble fraction, major ginsenosides, protopanaxatrol conversions, protopanaxadiol conversions as the fractions fractionated by C18 revers phase resin and various proportions of aqueous acetonitrile. We found that propanaxatriol conversions fraction one of the red ginseng samples inhibited in a concentration-dependent manner against MMP-2, and -9 expression levels in human fibroblast cells irradiated by UV light. By HPLC analysis, protopanaxtriol conversions fraction consisted on ginsenosides Rk3, F4, Rg6,and Rh4. These results suggest that dehydrates of protopanaxatriol ginsenoside from red ginseng have an antiwrinkle activity through inhibition of MMP-2, and -9 expression in skin.
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참고문헌 (13)
참고문헌 신청
Choi SW / 1998 / Signal transduction in aged skin cells / Kor. J. Invest. Dermatol 21 : 16 ~ 20
Fisher GJ / 1996 / Molecular basis of sun-induced premature ageingand retinoid antagonism / Nature 376 : 335 ~ 339
Fisher GJ / 1997 / Pathophysiology of premature skin aging induced by ultraviolet light / N. Eng. J. Med 337 : 1419 ~ 1428
Fisher GJ / 2002 / Mechanism of photoagaing and chronological skin againg / Arch. Dermatol 138 : 1462 ~ 1470
Hu B / 2013 / Bioactive peptides/chitosan nanoparticles enhance cellular antioxidant activity of (-)epigallocatechin3gallate / J. Agric. Food Chem : 875 ~ 881
Fisher GJ / 1996 / Molecular basis of sun-induced premature ageingand retinoid antagonism / Nature 376 : 335 ~ 339
Fisher GJ / 1997 / Pathophysiology of premature skin aging induced by ultraviolet light / N. Eng. J. Med 337 : 1419 ~ 1428
Fisher GJ / 2002 / Mechanism of photoagaing and chronological skin againg / Arch. Dermatol 138 : 1462 ~ 1470
Hu B / 2013 / Bioactive peptides/chitosan nanoparticles enhance cellular antioxidant activity of (-)epigallocatechin3gallate / J. Agric. Food Chem : 875 ~ 881
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